Airlines with flights from Knoxville to Chicago
There are three airlines with scheduled flights between TYS and ORD. Both American Airlines and United operates non-stop flights from Mc Ghee Tyson to Chicago O'Hare and the flight time is 2 hours and 5 minutes.
There are three airlines with scheduled flights between TYS and ORD. Both American Airlines and United operates non-stop flights from Mc Ghee Tyson to Chicago O'Hare and the flight time is 2 hours and 5 minutes. Choose airline
Direct
Non-stop
2h 5min
Direct
Non-stop
1h 59min
Via Detroit
3h 38min
Via Atlanta
3h 55min
Via Charlotte
4h 0min
Schedules
Non-stop with American Airlines
-
Total flight time: 2 hours and 5 minutes
-
One World Alliance
-
Chicago is a American Airlines hub.
-
35 flights per week
-
Embraer 170Canadair (Bombardier) Regional Jet 700 and Challenger 870Embraer 175
-
First class available
TYS
Direct
ORD
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
AA3726
07:15
07:15
07:15
07:15
07:15
07:46
07:15
AA6445
11:29
11:29
11:29
11:29
11:29
11:23
11:29
AA6456
13:13
13:13
13:13
13:13
13:13
13:03
13:13
AA3603
18:43
18:43
18:38
18:43
18:43
19:02
18:43
The timetable & schedule information was updated at 2026-04-21
Non-stop with United Airlines
-
Total flight time: 1 hour and 59 minutes
-
Chicago is a United Airlines hub (Largest hub ).
-
28 flights per week
-
Airbus A319Airbus A320Canadair (Bombardier) Regional Jet 550
-
Business and first class available
TYS
Direct
ORD
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
UA2805
06:00
06:00
06:00
06:00
06:00
06:00
06:00
UA4578
10:20
10:20
10:20
10:20
10:20
10:20
10:20
UA5654
13:54
13:54
13:54
13:54
13:54
13:54
13:54
UA5469
17:41
17:41
17:41
17:41
17:41
17:41
17:41
The timetable & schedule information was updated at 2026-04-21
Via Detroit with Delta Air Lines
-
Total flight time: 3h 38m - 6h 12m.
-
Sky Team Alliance
-
42 flights per week
TYS
Via DTW
ORD
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
DL5196
DL4683
DL4683
----
----
----
----
----
07:11
----
DL5196
DL3673
DL3673
07:11
07:11
07:11
07:11
07:11
----
07:11
DL5341
DL2358
DL2358
11:41
11:41
11:41
11:41
11:41
11:31
11:41
DL4698
DL1665
DL1665
15:59
15:59
15:59
15:59
15:59
15:59
15:59
DL4697
DL1665
DL1665
17:25
17:25
17:25
17:25
17:25
----
17:25
The timetable & schedule information was updated at 2026-04-21
Via Atlanta with Delta Air Lines
-
Total flight time: 3h 55m - 6h 16m.
-
Sky Team Alliance
-
227 flights per week
TYS
Via ATL
ORD
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
DL3015
DL1178
DL1178
05:40
05:40
05:40
05:40
05:40
----
05:40
DL3015
DL1147
DL1147
----
----
----
----
----
06:00
----
DL5317
DL2894
DL2894
07:33
07:33
07:33
07:33
07:33
07:33
07:33
DL5279
DL2894
DL2894
08:35
08:35
08:35
08:35
08:35
09:00
09:25
DL1290
DL1477
DL1477
10:26
10:26
----
10:26
10:26
10:26
10:26
DL4965
DL1477
DL1477
----
----
10:34
----
----
----
----
DL1743
DL2738
DL2738
11:55
11:55
11:55
11:55
11:55
----
11:55
DL4724
DL2879
DL2879
13:59
13:59
13:59
13:59
13:59
13:59
13:59
DL1148
DL2486
DL2486
15:54
15:54
15:54
15:54
15:54
----
15:54
DL2571
DL1139
DL1139
18:05
----
18:05
18:05
18:05
----
18:05
DL5416
DL1199
DL1199
----
19:43
19:43
----
----
----
----
DL3042
DL1199
DL1199
19:43
----
----
19:43
19:43
----
19:43
The timetable & schedule information was updated at 2026-04-21
Via Charlotte with American Airlines
-
Total flight time: 4h 00m - 6h 57m.
-
One World Alliance
-
Chicago is a American Airlines hub.
-
196 flights per week
-
Embraer 170Canadair (Bombardier) Regional Jet 700 and Challenger 870Embraer 175
TYS
Via CLT
ORD
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
AA5182
AA2843
AA2843
05:00
05:00
05:00
05:00
05:00
05:00
05:00
AA5954
AA1038
AA1038
06:55
06:55
06:55
06:55
06:55
06:55
06:55
AA5947
AA2530
AA2530
08:59
----
----
08:59
08:59
08:59
08:59
AA5950
AA2530
AA2530
11:01
11:01
11:01
11:01
11:01
11:01
11:01
AA5953
AA2907
AA2907
13:00
13:00
13:00
13:00
----
----
----
AA5831
AA2488
AA2488
15:40
15:40
15:40
15:40
15:40
15:40
15:40
AA6439
AA627
AA627
18:07
18:07
18:07
18:07
18:07
18:07
18:07
AA5957
AA3014
AA3014
19:59
----
19:59
19:59
19:59
19:59
19:59
The timetable & schedule information was updated at 2026-04-21
