Airlines with flights from Knoxville to Chicago

There are three airlines with scheduled flights between TYS and ORD. Both American Airlines and United operates non-stop flights from Mc Ghee Tyson to Chicago O'Hare and the flight time is 2 hours and 9 minutes.

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Schedules

American Airlines

Non-stop with American Airlines

  • Total flight time: 2 hours and 9 minutes
  • One World Alliance
  • Chicago is a American Airlines hub.
  • 28 flights per week
  • Canadair (Bombardier) Regional Jet 700 and Challenger 870
    Embraer 175
    Embraer 170
  • First class available
TYS
Direct
ORD
 
Flight
Mon
Aug 3
Tue
Aug 4
Wed
Aug 5
Thu
Aug 6
Fri
Aug 7
Sat
Aug 8
Sun
Aug 9
AA6216
07:02
07:02
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AA6187
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07:23
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AA3837
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07:34
07:34
07:59
07:34
AA6445
11:35
11:35
11:40
11:40
11:40
11:40
11:36
AA5014
13:00
13:00
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AA3571
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13:21
13:21
13:21
13:16
13:21
AA3783
18:32
18:32
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AA4970
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----
18:52
18:52
18:52
18:52
19:18
SHOW RETURN SCHEDULE
CHECK PRICES FOR TYS - ORD

The timetable & schedule information was updated at 2026-04-21

United Airlines

Non-stop with United Airlines

  • Total flight time: 1 hour and 58 minutes
  • Chicago is a United Airlines hub (Largest hub ).
  • 27 flights per week
  • Boeing 737-900 Passenger
    Canadair (Bombardier) Regional Jet 550
    Embraer 175 (Enhanced Winglets)
  • Business and first class available
TYS
Direct
ORD
 
Flight
Mon
Aug 3
Tue
Aug 4
Wed
Aug 5
Thu
Aug 6
Fri
Aug 7
Sat
Aug 8
Sun
Aug 9
UA2483
06:00
06:00
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06:00
06:00
06:00
06:00
UA4584
10:18
10:18
10:18
10:18
10:18
10:18
10:18
UA5617
13:54
13:54
13:54
13:54
13:54
13:54
13:54
UA6000
17:45
17:45
17:45
17:45
17:45
17:50
17:45
SHOW RETURN SCHEDULE
CHECK PRICES FOR TYS - ORD

The timetable & schedule information was updated at 2026-04-21

Delta Air Lines

Via Detroit with Delta Air Lines

  • Total flight time: 3h 38m - 6h 12m.
  • Sky Team Alliance
  • 42 flights per week
TYS
 
Via DTW
 
ORD
 
Flight
Mon
Aug 3
Tue
Aug 4
Wed
Aug 5
Thu
Aug 6
Fri
Aug 7
Sat
Aug 8
Sun
Aug 9
DL5196
DL3673
07:11
07:11
07:11
07:11
07:11
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07:11
DL5196
DL4683
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07:11
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DL5341
DL2358
11:41
11:41
11:41
11:41
11:41
11:31
11:41
DL4698
DL1665
15:59
15:59
15:59
15:59
15:59
15:59
15:59
DL4697
DL1665
17:25
17:25
17:25
17:25
17:25
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17:25
SHOW RETURN SCHEDULE
CHECK PRICES FOR TYS - ORD

The timetable & schedule information was updated at 2026-04-21

Delta Air Lines

Via Atlanta with Delta Air Lines

  • Total flight time: 3h 55m - 6h 16m.
  • Sky Team Alliance
  • 227 flights per week
TYS
 
Via ATL
 
ORD
 
Flight
Mon
Aug 3
Tue
Aug 4
Wed
Aug 5
Thu
Aug 6
Fri
Aug 7
Sat
Aug 8
Sun
Aug 9
DL3015
DL1178
05:40
05:40
05:40
05:40
05:40
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05:40
DL3015
DL1147
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06:00
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DL5317
DL2894
07:33
07:33
07:33
07:33
07:33
07:33
07:33
DL5279
DL2894
08:35
08:35
08:35
08:35
08:35
09:00
09:25
DL1290
DL1477
10:26
10:26
10:26
10:26
10:26
10:26
10:26
DL1743
DL2738
11:55
11:55
11:55
11:55
11:55
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11:55
DL4724
DL2879
13:59
13:59
13:59
13:59
13:59
13:59
13:59
DL1148
DL2486
15:54
15:54
15:54
15:54
15:54
16:07
15:54
DL2571
DL1139
18:05
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18:05
18:05
18:05
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18:05
DL4641
DL1199
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18:07
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DL5416
DL1199
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19:43
19:43
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DL3042
DL1199
19:43
----
----
19:43
19:43
----
19:43
SHOW RETURN SCHEDULE
CHECK PRICES FOR TYS - ORD

The timetable & schedule information was updated at 2026-04-21

American Airlines

Via Charlotte with American Airlines

  • Total flight time: 4h 00m - 6h 57m.
  • One World Alliance
  • Chicago is a American Airlines hub.
  • 196 flights per week
  • Canadair (Bombardier) Regional Jet 700 and Challenger 870
    Embraer 175
    Embraer 170
TYS
 
Via CLT
 
ORD
 
Flight
Mon
Aug 3
Tue
Aug 4
Wed
Aug 5
Thu
Aug 6
Fri
Aug 7
Sat
Aug 8
Sun
Aug 9
AA5847
AA2843
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----
05:00
----
05:00
05:00
AA5182
AA2843
05:03
05:03
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AA5847
AA1038
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06:15
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06:15
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AA5954
AA1038
06:42
06:42
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AA5087
AA1038
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07:00
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07:00
07:00
AA5182
AA2742
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08:10
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08:10
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AA5947
AA2908
08:56
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AA6093
AA2530
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10:08
09:03
10:08
09:03
09:03
AA5950
AA836
11:03
11:03
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AA6094
AA2423
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12:09
11:17
12:09
11:17
11:17
AA6095
AA3218
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----
13:02
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12:52
13:02
AA5953
AA2907
13:00
13:00
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AA6096
AA536
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13:56
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13:56
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AA5831
AA2488
15:40
15:40
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AA6097
AA2488
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16:22
15:41
16:22
15:41
15:41
AA6281
AA815
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18:05
18:05
18:05
18:05
18:05
AA6098
AA627
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----
19:16
20:11
19:16
20:11
20:11
AA5957
AA3014
20:05
----
----
----
----
----
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SHOW RETURN SCHEDULE
CHECK PRICES FOR TYS - ORD

The timetable & schedule information was updated at 2026-04-21

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Flight data on this page was last updated on 2026-07-13
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