Airlines with flights from Knoxville to Houston

There are four airlines with scheduled flights between TYS and HOU. Allegiant is the only airline with non-stop flights from Mc Ghee Tyson to Hobby Airport and the flight time is 2 hours and 19 minutes.

Choose airline

Schedules

Allegiant Air

Non-stop with Allegiant Air

  • Total flight time: 2 hours and 19 minutes
  • Low-cost airline
  • Knoxville is a Allegiant Air focus city (Operating base).
  • 2 flights per week
  • Airbus A320
TYS
Direct
HOU

The timetable & schedule information was updated at 2026-04-21

Southwest Airlines

Via Nashville with Southwest Airlines

  • Total flight time: 3h 50m - 8h 00m.
  • Low-cost airline
  • Houston is a Southwest Airlines focus city (Operating base).
  • 33 flights per week
TYS
 
Via BNA
 
HOU

The timetable & schedule information was updated at 2026-04-21

Delta Air Lines

Via Atlanta with Delta Air Lines

  • Total flight time: 3h 53m - 6h 14m.
  • Sky Team Alliance
  • 137 flights per week
TYS
 
Via ATL
 
HOU
 
Flight
Mon
Jun 8
Tue
Jun 9
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Jun 10
Thu
Jun 11
Fri
Jun 12
Sat
Jun 13
Sun
Jun 14
DL3015
DL1509
05:40
05:40
05:40
05:40
05:40
06:00
05:40
DL5317
DL1195
07:33
07:33
07:33
07:33
07:33
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07:33
DL5279
DL1195
08:35
08:35
08:35
08:35
08:35
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DL1743
DL2381
11:55
11:55
11:55
11:55
11:55
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11:55
DL2571
DL2051
18:05
18:05
18:05
18:05
18:05
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18:05
DL4641
DL2051
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18:07
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SHOW RETURN SCHEDULE
CHECK PRICES FOR TYS - HOU

The timetable & schedule information was updated at 2026-04-21

Southwest Airlines

Via Dallas with Southwest Airlines

  • Total flight time: 4h 05m - 6h 55m.
  • Low-cost airline
  • Houston is a Southwest Airlines focus city (Operating base).
  • 22 flights per week
TYS
 
Via DAL
 
HOU

The timetable & schedule information was updated at 2026-04-21

American Airlines

Via Dallas with American Airlines

  • Total flight time: 4h 29m - 6h 44m.
  • One World Alliance
  • 97 flights per week
TYS
 
Via DFW
 
HOU

The timetable & schedule information was updated at 2026-04-21

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Flight data on this page was last updated on 2026-05-25