Airlines with flights from Houston to Knoxville
There are four airlines with scheduled flights between HOU and TYS. Allegiant is the only airline with non-stop flights from Hobby Airport to Mc Ghee Tyson and the flight time is 2 hours and 4 minutes.
Choose airline
Schedules
Non-stop with Allegiant Air
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Total flight time: 2 hours and 4 minutes
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Low-cost airline
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Knoxville is a Allegiant Air focus city (Operating base).
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2 flights per week
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Airbus A320
HOU
Direct
TYS
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
G41415
19:31
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19:44
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The timetable & schedule information was updated at 2026-04-22
Via Nashville with Southwest Airlines
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Total flight time: 3h 35m - 7h 45m.
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Low-cost airline
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Houston is a Southwest Airlines focus city (Operating base).
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38 flights per week
HOU
Via BNA
TYS
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
WN1954
WN790
WN790
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07:05
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WN1954
WN4206
WN4206
07:10
07:20
07:20
07:10
07:10
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07:10
WN1712
WN694
WN694
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13:30
13:30
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WN1712
WN432
WN432
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----
----
----
----
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14:30
WN410
WN694
WN694
14:45
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14:45
14:45
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WN5080
WN432
WN432
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15:45
The timetable & schedule information was updated at 2026-04-22
Via Atlanta with Delta Air Lines
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Total flight time: 3h 43m - 6h 08m.
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Sky Team Alliance
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113 flights per week
HOU
Via ATL
TYS
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
DL2557
DL1743
DL1743
06:00
06:00
06:00
06:00
06:00
----
06:00
DL2557
DL4724
DL4724
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06:00
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DL1509
DL4641
DL4641
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10:16
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DL1195
DL3042
DL3042
12:58
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12:58
12:58
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12:58
DL1195
DL5416
DL5416
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12:58
12:58
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DL2381
DL2081
DL2081
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17:14
17:14
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17:14
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DL2381
DL3072
DL3072
17:14
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17:14
17:14
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17:14
The timetable & schedule information was updated at 2026-04-22
Via Dallas with Southwest Airlines
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Total flight time: 3h 50m - 7h 10m.
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Low-cost airline
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Houston is a Southwest Airlines focus city (Operating base).
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19 flights per week
HOU
Via DAL
TYS
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
WN4
WN3319
WN3319
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07:00
07:00
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----
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WN10
WN3319
WN3319
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08:30
08:30
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WN14
WN3319
WN3319
09:30
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09:30
09:30
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The timetable & schedule information was updated at 2026-04-22
Via Dallas with American Airlines
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Total flight time: 4h 04m - 6h 20m.
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One World Alliance
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229 flights per week
HOU
Via DFW
TYS
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
AA3395
AA2873
AA2873
06:03
06:03
06:03
06:03
06:03
06:03
06:03
AA3573
AA2876
AA2876
09:30
09:30
09:30
09:30
09:30
09:30
09:30
AA6413
AA644
AA644
12:50
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12:50
12:50
12:50
12:50
AA5002
AA5453
AA5453
16:15
16:15
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16:15
16:15
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16:15
AA6385
AA1081
AA1081
18:39
18:40
18:39
18:39
18:39
18:39
18:39
The timetable & schedule information was updated at 2026-04-22

There are four airlines with scheduled flights between HOU and TYS. Allegiant is the only airline with non-stop flights from Hobby Airport to Mc Ghee Tyson and the flight time is 2 hours and 4 minutes.