Airlines with flights from Houston to Knoxville

There are four airlines with scheduled flights between HOU and TYS. Allegiant is the only airline with non-stop flights from Hobby Airport to Mc Ghee Tyson and the flight time is 2 hours and 4 minutes.

Choose airline

Schedules

Allegiant Air

Non-stop with Allegiant Air

  • Total flight time: 2 hours and 4 minutes
  • Low-cost airline
  • Knoxville is a Allegiant Air focus city (Operating base).
  • 2 flights per week
  • Airbus A320
HOU
Direct
TYS

The timetable & schedule information was updated at 2026-04-22

Southwest Airlines

Via Nashville with Southwest Airlines

  • Total flight time: 3h 35m - 7h 45m.
  • Low-cost airline
  • Houston is a Southwest Airlines focus city (Operating base).
  • 38 flights per week
HOU
 
Via BNA
 
TYS
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
WN1954
WN790
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07:05
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WN1954
WN4206
07:10
07:20
07:20
07:10
07:10
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07:10
WN1712
WN694
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13:30
13:30
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WN1712
WN432
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14:30
WN410
WN694
14:45
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14:45
14:45
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WN5080
WN432
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15:45
SHOW RETURN SCHEDULE
CHECK PRICES FOR HOU - TYS

The timetable & schedule information was updated at 2026-04-22

Delta Air Lines

Via Atlanta with Delta Air Lines

  • Total flight time: 3h 43m - 6h 08m.
  • Sky Team Alliance
  • 113 flights per week
HOU
 
Via ATL
 
TYS
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
DL2557
DL1743
06:00
06:00
06:00
06:00
06:00
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06:00
DL2557
DL4724
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06:00
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DL1509
DL4641
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10:16
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DL1195
DL3042
12:58
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12:58
12:58
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12:58
DL1195
DL5416
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12:58
12:58
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DL2381
DL2081
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17:14
17:14
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17:14
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DL2381
DL3072
17:14
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17:14
17:14
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17:14
SHOW RETURN SCHEDULE
CHECK PRICES FOR HOU - TYS

The timetable & schedule information was updated at 2026-04-22

Southwest Airlines

Via Dallas with Southwest Airlines

  • Total flight time: 3h 50m - 7h 10m.
  • Low-cost airline
  • Houston is a Southwest Airlines focus city (Operating base).
  • 19 flights per week
HOU
 
Via DAL
 
TYS

The timetable & schedule information was updated at 2026-04-22

American Airlines

Via Dallas with American Airlines

  • Total flight time: 4h 04m - 6h 20m.
  • One World Alliance
  • 229 flights per week
HOU
 
Via DFW
 
TYS
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
AA3395
AA2873
06:03
06:03
06:03
06:03
06:03
06:03
06:03
AA3573
AA2876
09:30
09:30
09:30
09:30
09:30
09:30
09:30
AA6413
AA644
12:50
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12:50
12:50
12:50
12:50
AA5002
AA5453
16:15
16:15
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16:15
16:15
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16:15
AA6385
AA1081
18:39
18:40
18:39
18:39
18:39
18:39
18:39
SHOW RETURN SCHEDULE
CHECK PRICES FOR HOU - TYS

The timetable & schedule information was updated at 2026-04-22

Staying up-to-date with the airlines

At Airlineinformation.com you can learn all about the airlines operating around the world together with their destinations and where they operate. You will get a transparent overview of airlines with scheduled flights between any two destinations with non-stop or 1-stop flights regardless of price or availability.
Flight data on this page was last updated on 2026-06-02