Airlines with flights from Knoxville to Key West

There are three airlines with scheduled flights between TYS and EYW. Allegiant is the only airline with non-stop flights from Mc Ghee Tyson to Key West International and the flight time is 2 hours and 7 minutes.

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Schedules

Allegiant Air

Non-stop with Allegiant Air

  • Total flight time: 2 hours and 7 minutes
  • Low-cost airline
  • Knoxville is a Allegiant Air focus city (Operating base).
  • 2 flights per week
  • Airbus A320
TYS
Direct
EYW
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
G41400
07:30
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G41411
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07:30
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The timetable & schedule information was updated at 2026-04-21

Delta Air Lines

Via Atlanta with Delta Air Lines

  • Total flight time: 3h 39m - 6h 05m.
  • Sky Team Alliance
  • 184 flights per week
TYS
 
Via ATL
 
EYW
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
DL3015
DL1281
05:40
05:40
05:40
05:40
05:40
06:00
05:40
DL5317
DL1671
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07:33
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DL5317
DL1472
07:33
07:33
07:33
07:33
07:33
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07:33
DL5279
DL1472
08:35
08:35
08:35
08:35
08:35
09:00
09:25
DL1743
DL2168
11:55
11:55
11:55
11:55
11:55
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11:55
DL4724
DL2815
13:59
13:59
13:59
13:59
13:59
13:59
13:59
DL1148
DL2815
15:54
15:54
15:54
15:54
15:54
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15:54
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The timetable & schedule information was updated at 2026-04-21

American Airlines

Via Miami with American Airlines

  • Total flight time: 3h 39m - 6h 08m.
  • One World Alliance
  • 15 flights per week
TYS
 
Via MIA
 
EYW
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
AA2730
AA3515
06:00
06:00
06:00
06:00
06:00
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06:00
AA2730
AA4725
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06:00
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CHECK PRICES FOR TYS - EYW

The timetable & schedule information was updated at 2026-04-21

American Airlines

Via Charlotte with American Airlines

  • Total flight time: 4h 06m - 6h 43m.
  • One World Alliance
  • 143 flights per week
TYS
 
Via CLT
 
EYW
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
AA5954
AA1826
06:55
06:55
06:55
06:55
06:55
06:55
06:55
AA5950
AA3519
11:01
11:01
11:01
11:01
11:01
11:01
11:01
AA5953
AA2533
13:00
13:00
13:00
13:00
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SHOW RETURN SCHEDULE
CHECK PRICES FOR TYS - EYW

The timetable & schedule information was updated at 2026-04-21

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Flight data on this page was last updated on 2026-06-02
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