Airlines with flights from Key West to Knoxville
There are three airlines with scheduled flights between EYW and TYS. Allegiant is the only airline with non-stop flights from Key West International to Mc Ghee Tyson and the flight time is 2 hours and 14 minutes.
Choose airline
Schedules
Non-stop with Allegiant Air
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Total flight time: 2 hours and 14 minutes
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Low-cost airline
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Knoxville is a Allegiant Air focus city (Operating base).
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2 flights per week
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Airbus A320
EYW
Direct
TYS
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
G41397
10:31
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10:31
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The timetable & schedule information was updated at 2026-04-21
Via Miami with American Airlines
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Total flight time: 3h 40m - 5h 42m.
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One World Alliance
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30 flights per week
EYW
Via MIA
TYS
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
AA4732
AA3457
AA3457
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13:39
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AA3518
AA3457
AA3457
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13:39
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AA3517
AA2716
AA2716
19:40
19:40
19:40
19:40
19:40
19:49
19:40
The timetable & schedule information was updated at 2026-04-21
Via Atlanta with Delta Air Lines
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Total flight time: 3h 42m - 6h 05m.
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Sky Team Alliance
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122 flights per week
EYW
Via ATL
TYS
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
DL1072
DL4724
DL4724
07:45
07:45
07:45
07:45
07:45
07:45
07:45
DL1281
DL4641
DL4641
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11:52
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DL1281
DL2571
DL2571
11:58
11:58
11:58
11:58
11:58
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11:58
DL1671
DL4641
DL4641
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----
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13:08
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DL1472
DL3042
DL3042
14:24
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14:24
14:24
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14:24
DL1472
DL5416
DL5416
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14:24
14:24
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14:24
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DL2168
DL3072
DL3072
18:24
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18:24
18:24
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18:24
DL2168
DL2081
DL2081
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18:24
18:24
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18:24
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The timetable & schedule information was updated at 2026-04-21
Via Charlotte with American Airlines
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Total flight time: 4h 04m - 6h 44m.
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One World Alliance
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103 flights per week
EYW
Via CLT
TYS
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
AA1826
AA6439
AA6439
13:01
13:01
13:01
13:01
13:01
13:01
13:01
AA3519
AA5909
AA5909
16:44
16:44
16:44
16:44
16:44
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16:44
AA3519
AA5511
AA5511
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17:53
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AA2533
AA5511
AA5511
19:29
19:29
19:29
19:29
19:29
19:29
19:29
The timetable & schedule information was updated at 2026-04-21

There are three airlines with scheduled flights between EYW and TYS. Allegiant is the only airline with non-stop flights from Key West International to Mc Ghee Tyson and the flight time is 2 hours and 14 minutes.