Airlines with flights from Key West to Knoxville

There are three airlines with scheduled flights between EYW and TYS. Allegiant is the only airline with non-stop flights from Key West International to Mc Ghee Tyson and the flight time is 2 hours and 14 minutes.

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Schedules

Allegiant Air

Non-stop with Allegiant Air

  • Total flight time: 2 hours and 14 minutes
  • Low-cost airline
  • Knoxville is a Allegiant Air focus city (Operating base).
  • 2 flights per week
  • Airbus A320
EYW
Direct
TYS

The timetable & schedule information was updated at 2026-04-21

American Airlines

Via Miami with American Airlines

  • Total flight time: 3h 40m - 5h 42m.
  • One World Alliance
  • 30 flights per week
EYW
 
Via MIA
 
TYS

The timetable & schedule information was updated at 2026-04-21

Delta Air Lines

Via Atlanta with Delta Air Lines

  • Total flight time: 3h 42m - 6h 05m.
  • Sky Team Alliance
  • 122 flights per week
EYW
 
Via ATL
 
TYS
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
DL1072
DL4724
07:45
07:45
07:45
07:45
07:45
07:45
07:45
DL1281
DL4641
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11:52
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DL1281
DL2571
11:58
11:58
11:58
11:58
11:58
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11:58
DL1671
DL4641
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13:08
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DL1472
DL3042
14:24
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14:24
14:24
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14:24
DL1472
DL5416
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14:24
14:24
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14:24
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DL2168
DL3072
18:24
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18:24
18:24
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18:24
DL2168
DL2081
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18:24
18:24
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18:24
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SHOW RETURN SCHEDULE
CHECK PRICES FOR EYW - TYS

The timetable & schedule information was updated at 2026-04-21

American Airlines

Via Charlotte with American Airlines

  • Total flight time: 4h 04m - 6h 44m.
  • One World Alliance
  • 103 flights per week
EYW
 
Via CLT
 
TYS

The timetable & schedule information was updated at 2026-04-21

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Flight data on this page was last updated on 2026-06-02