Airlines with flights from Knoxville to Detroit

There are four airlines with scheduled flights between TYS and DTW. Delta is the only airline with non-stop flights from Mc Ghee Tyson to Detroit Metropolitan Airport and the flight time is 1 hour and 45 minutes.

Choose airline

Schedules

Delta Air Lines

Non-stop with Delta Air Lines

  • Total flight time: 1 hour and 45 minutes
  • Sky Team Alliance
  • Detroit is a Delta Air Lines hub.
  • 29 flights per week
  • Canadair (Bombardier) Regional Jet 700 and Challenger 870
    Canadair (Bombardier) Regional Jet 900
  • First class available
TYS
Direct
DTW

The timetable & schedule information was updated at 2026-04-21

American Airlines

Via Charlotte with American Airlines

  • Total flight time: 3h 29m - 6h 18m.
  • One World Alliance
  • 139 flights per week
TYS
 
Via CLT
 
DTW
 
Flight
Mon
Jul 13
Tue
Jul 14
Wed
Jul 15
Thu
Jul 16
Fri
Jul 17
Sat
Jul 18
Sun
Jul 19
AA5182
AA1791
05:03
----
----
05:03
05:03
05:03
05:03
AA5947
AA1781
08:56
----
----
08:56
08:56
----
08:56
AA5950
AA1770
11:03
11:03
11:03
11:03
11:03
11:03
11:03
AA5953
AA1794
13:00
13:00
13:00
13:00
----
----
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AA6439
AA419
18:07
18:07
18:07
18:07
18:07
18:07
18:07
AA5957
AA370
20:05
----
20:05
20:05
20:05
20:05
20:05
SHOW RETURN SCHEDULE
CHECK PRICES FOR TYS - DTW

The timetable & schedule information was updated at 2026-04-21

Southwest Airlines

Via Nashville with Southwest Airlines

  • Total flight time: 3h 30m - 5h 45m.
  • Low-cost airline
  • 32 flights per week
TYS
 
Via BNA
 
DTW

The timetable & schedule information was updated at 2026-04-21

Delta Air Lines

Via Atlanta with Delta Air Lines

  • Total flight time: 3h 42m - 6h 04m.
  • Sky Team Alliance
  • Detroit is a Delta Air Lines hub.
  • 250 flights per week
  • Canadair (Bombardier) Regional Jet 700 and Challenger 870
    Canadair (Bombardier) Regional Jet 900
TYS
 
Via ATL
 
DTW
 
Flight
Mon
Jul 13
Tue
Jul 14
Wed
Jul 15
Thu
Jul 16
Fri
Jul 17
Sat
Jul 18
Sun
Jul 19
DL3015
DL1646
05:40
05:40
05:40
05:40
05:40
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05:40
DL3015
DL1298
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----
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----
----
06:00
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DL5317
DL1240
07:33
07:33
07:33
07:33
07:33
07:33
07:33
DL5279
DL1240
08:35
08:35
08:35
08:35
08:35
----
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DL1290
DL1031
10:26
10:26
10:26
10:26
10:26
10:26
10:26
DL1743
DL1031
11:55
11:55
11:55
11:55
11:55
----
11:55
DL4724
DL2067
13:59
13:59
13:59
13:59
13:59
13:59
13:59
DL1148
DL1478
15:54
15:54
15:54
15:54
15:54
----
15:54
DL2571
DL1232
18:05
18:05
18:05
18:05
18:05
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18:05
DL4641
DL1232
----
----
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----
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18:07
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DL3042
DL651
19:43
----
----
19:43
19:43
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19:43
DL5416
DL651
----
19:43
19:43
----
----
----
----
SHOW RETURN SCHEDULE
CHECK PRICES FOR TYS - DTW

The timetable & schedule information was updated at 2026-04-21

American Airlines

Via Chicago with American Airlines

  • Total flight time: 3h 53m - 6h 43m.
  • One World Alliance
  • 69 flights per week
TYS
 
Via ORD
 
DTW

The timetable & schedule information was updated at 2026-04-21

Staying up-to-date with the airlines

At Airlineinformation.com you can learn all about the airlines operating around the world together with their destinations and where they operate. You will get a transparent overview of airlines with scheduled flights between any two destinations with non-stop or 1-stop flights regardless of price or availability.
Flight data on this page was last updated on 2026-06-29