Airlines with flights from Knoxville to Detroit
There are four airlines with scheduled flights between TYS and DTW. Delta is the only airline with non-stop flights from Mc Ghee Tyson to Detroit Metropolitan Airport and the flight time is 1 hour and 45 minutes.
Choose airline
Schedules
Non-stop with Delta Air Lines
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Total flight time: 1 hour and 45 minutes
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Sky Team Alliance
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Detroit is a Delta Air Lines hub.
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29 flights per week
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Canadair (Bombardier) Regional Jet 700 and Challenger 870Canadair (Bombardier) Regional Jet 900
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First class available
TYS
Direct
DTW
W29, Jul 13 - Jul 19
Flight
Mon
Jul 13
Tue
Jul 14
Wed
Jul 15
Thu
Jul 16
Fri
Jul 17
Sat
Jul 18
Sun
Jul 19
DL5196
07:15
07:15
07:15
07:15
07:15
07:15
07:15
DL5341
11:41
11:41
11:41
11:41
11:41
11:31
11:41
DL4698
15:59
15:59
15:59
15:59
15:59
15:59
15:59
DL4697
17:23
17:23
17:23
17:23
17:23
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17:23
The timetable & schedule information was updated at 2026-04-21
Via Charlotte with American Airlines
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Total flight time: 3h 29m - 6h 18m.
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One World Alliance
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139 flights per week
TYS
Via CLT
DTW
W29, Jul 13 - Jul 19
Flight
Mon
Jul 13
Tue
Jul 14
Wed
Jul 15
Thu
Jul 16
Fri
Jul 17
Sat
Jul 18
Sun
Jul 19
AA5182
AA1791
AA1791
05:03
----
----
05:03
05:03
05:03
05:03
AA5947
AA1781
AA1781
08:56
----
----
08:56
08:56
----
08:56
AA5950
AA1770
AA1770
11:03
11:03
11:03
11:03
11:03
11:03
11:03
AA5953
AA1794
AA1794
13:00
13:00
13:00
13:00
----
----
----
AA6439
AA419
AA419
18:07
18:07
18:07
18:07
18:07
18:07
18:07
AA5957
AA370
AA370
20:05
----
20:05
20:05
20:05
20:05
20:05
The timetable & schedule information was updated at 2026-04-21
Via Nashville with Southwest Airlines
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Total flight time: 3h 30m - 5h 45m.
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Low-cost airline
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32 flights per week
TYS
Via BNA
DTW
W29, Jul 13 - Jul 19
Flight
Mon
Jul 13
Tue
Jul 14
Wed
Jul 15
Thu
Jul 16
Fri
Jul 17
Sat
Jul 18
Sun
Jul 19
WN1768
WN509
WN509
19:45
18:55
18:55
19:45
19:45
18:55
19:00
The timetable & schedule information was updated at 2026-04-21
Via Atlanta with Delta Air Lines
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Total flight time: 3h 42m - 6h 04m.
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Sky Team Alliance
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Detroit is a Delta Air Lines hub.
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250 flights per week
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Canadair (Bombardier) Regional Jet 700 and Challenger 870Canadair (Bombardier) Regional Jet 900
TYS
Via ATL
DTW
W29, Jul 13 - Jul 19
Flight
Mon
Jul 13
Tue
Jul 14
Wed
Jul 15
Thu
Jul 16
Fri
Jul 17
Sat
Jul 18
Sun
Jul 19
DL3015
DL1646
DL1646
05:40
05:40
05:40
05:40
05:40
----
05:40
DL3015
DL1298
DL1298
----
----
----
----
----
06:00
----
DL5317
DL1240
DL1240
07:33
07:33
07:33
07:33
07:33
07:33
07:33
DL5279
DL1240
DL1240
08:35
08:35
08:35
08:35
08:35
----
----
DL1290
DL1031
DL1031
10:26
10:26
10:26
10:26
10:26
10:26
10:26
DL1743
DL1031
DL1031
11:55
11:55
11:55
11:55
11:55
----
11:55
DL4724
DL2067
DL2067
13:59
13:59
13:59
13:59
13:59
13:59
13:59
DL1148
DL1478
DL1478
15:54
15:54
15:54
15:54
15:54
----
15:54
DL2571
DL1232
DL1232
18:05
18:05
18:05
18:05
18:05
----
18:05
DL4641
DL1232
DL1232
----
----
----
----
----
18:07
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DL3042
DL651
DL651
19:43
----
----
19:43
19:43
----
19:43
DL5416
DL651
DL651
----
19:43
19:43
----
----
----
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The timetable & schedule information was updated at 2026-04-21
Via Chicago with American Airlines
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Total flight time: 3h 53m - 6h 43m.
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One World Alliance
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69 flights per week
TYS
Via ORD
DTW
W29, Jul 13 - Jul 19
Flight
Mon
Jul 13
Tue
Jul 14
Wed
Jul 15
Thu
Jul 16
Fri
Jul 17
Sat
Jul 18
Sun
Jul 19
AA5379
AA3498
AA3498
07:06
07:06
07:06
07:06
07:06
07:02
07:06
AA6445
AA3980
AA3980
11:28
11:28
11:28
11:28
11:28
11:23
11:28
The timetable & schedule information was updated at 2026-04-21

There are four airlines with scheduled flights between TYS and DTW. Delta is the only airline with non-stop flights from Mc Ghee Tyson to Detroit Metropolitan Airport and the flight time is 1 hour and 45 minutes.
Via Dulles with United