Airlines with flights from Detroit to Knoxville
There are four airlines with scheduled flights between DTW and TYS. Delta is the only airline with non-stop flights from Detroit Metropolitan Airport to Mc Ghee Tyson and the flight time is 1 hour and 41 minutes.
Choose airline
Schedules
Non-stop with Delta Air Lines
-
Total flight time: 1 hour and 41 minutes
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Sky Team Alliance
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Detroit is a Delta Air Lines hub.
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29 flights per week
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Canadair (Bombardier) Regional Jet 900Canadair (Bombardier) Regional Jet 700 and Challenger 870
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First class available
DTW
Direct
TYS
W29, Jul 13 - Jul 19
Flight
Mon
Jul 13
Tue
Jul 14
Wed
Jul 15
Thu
Jul 16
Fri
Jul 17
Sat
Jul 18
Sun
Jul 19
DL5347
08:40
08:40
08:40
08:40
08:40
08:32
08:40
DL4698
13:40
13:40
13:40
13:40
13:40
13:40
13:40
DL4941
16:13
16:13
16:13
16:13
16:13
----
16:13
DL5138
19:59
19:59
19:59
19:59
19:59
19:59
19:59
The timetable & schedule information was updated at 2026-04-21
Via Nashville with Southwest Airlines
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Total flight time: 3h 25m - 5h 25m.
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Low-cost airline
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18 flights per week
DTW
Via BNA
TYS
W29, Jul 13 - Jul 19
Flight
Mon
Jul 13
Tue
Jul 14
Wed
Jul 15
Thu
Jul 16
Fri
Jul 17
Sat
Jul 18
Sun
Jul 19
WN4581
WN790
WN790
----
----
----
----
----
06:35
----
WN4581
WN4206
WN4206
----
06:40
06:40
----
----
----
----
The timetable & schedule information was updated at 2026-04-21
Via Charlotte with American Airlines
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Total flight time: 3h 30m - 6h 16m.
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One World Alliance
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161 flights per week
DTW
Via CLT
TYS
W29, Jul 13 - Jul 19
Flight
Mon
Jul 13
Tue
Jul 14
Wed
Jul 15
Thu
Jul 16
Fri
Jul 17
Sat
Jul 18
Sun
Jul 19
AA387
AA5950
AA5950
06:00
06:00
06:00
06:00
06:00
06:00
06:00
AA1439
AA5953
AA5953
07:00
----
----
07:00
----
----
----
AA1791
AA5831
AA5831
10:01
10:01
10:01
10:01
10:01
10:01
10:01
AA1781
AA6439
AA6439
13:41
13:41
13:41
13:41
13:41
----
13:41
AA1770
AA5909
AA5909
16:17
16:17
16:17
16:17
16:17
16:37
16:17
AA1794
AA5511
AA5511
19:58
19:58
19:58
19:58
19:58
19:58
19:58
The timetable & schedule information was updated at 2026-04-21
Via Atlanta with Delta Air Lines
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Total flight time: 3h 37m - 6h 03m.
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Sky Team Alliance
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Detroit is a Delta Air Lines hub.
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277 flights per week
-
Canadair (Bombardier) Regional Jet 900Canadair (Bombardier) Regional Jet 700 and Challenger 870
DTW
Via ATL
TYS
W29, Jul 13 - Jul 19
Flight
Mon
Jul 13
Tue
Jul 14
Wed
Jul 15
Thu
Jul 16
Fri
Jul 17
Sat
Jul 18
Sun
Jul 19
DL2375
DL1290
DL1290
05:20
05:20
05:20
05:20
05:20
05:20
05:20
DL1611
DL1743
DL1743
06:20
06:20
06:20
06:20
06:20
----
06:20
DL965
DL4724
DL4724
----
----
07:20
----
DL965
DL1743
DL1743
07:20
07:20
07:20
07:20
07:20
----
07:20
DL1653
DL4724
DL4724
08:25
08:25
08:25
08:25
08:25
08:25
08:25
DL2777
DL4724
DL4724
09:25
09:25
09:25
09:25
09:25
----
09:25
DL2856
DL1148
DL1148
10:25
10:25
10:25
10:25
10:25
----
10:31
DL2188
DL2571
DL2571
12:25
12:25
12:25
12:25
12:25
----
12:25
DL2188
DL4641
DL4641
----
----
----
----
----
12:25
----
DL1228
DL5416
DL5416
----
14:59
14:59
----
----
----
----
DL1228
DL3042
DL3042
14:59
----
----
14:59
14:59
----
14:59
DL1467
DL5416
DL5416
----
----
----
----
----
14:59
----
DL1467
DL5203
DL5203
15:59
15:59
15:59
15:59
15:59
----
15:59
DL2053
DL2081
DL2081
----
18:38
18:38
----
----
17:59
----
DL2053
DL3072
DL3072
18:38
----
----
18:38
18:38
----
18:38
The timetable & schedule information was updated at 2026-04-21
Via Chicago with American Airlines
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Total flight time: 3h 45m - 6h 16m.
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One World Alliance
-
90 flights per week
DTW
Via ORD
TYS
W29, Jul 13 - Jul 19
Flight
Mon
Jul 13
Tue
Jul 14
Wed
Jul 15
Thu
Jul 16
Fri
Jul 17
Sat
Jul 18
Sun
Jul 19
AA6465
AA6445
AA6445
06:34
06:34
06:34
06:34
06:34
06:33
06:36
AA3498
AA5378
AA5378
13:04
13:04
13:04
13:04
13:04
13:04
13:04
AA3980
AA5341
AA5341
17:27
17:27
17:27
17:27
17:27
17:27
17:27
The timetable & schedule information was updated at 2026-04-21

There are four airlines with scheduled flights between DTW and TYS. Delta is the only airline with non-stop flights from Detroit Metropolitan Airport to Mc Ghee Tyson and the flight time is 1 hour and 41 minutes.
Via Dulles with United