Airlines with flights from Saint Louis to San Diego

There are five airlines with scheduled flights between STL and SAN. Southwest is the only airline with non-stop flights from Saint Louis Airport to San Diego International Airport and the flight time is 3 hours and 55 minutes.

Choose airline

Schedules

Southwest Airlines

Non-stop with Southwest Airlines

  • Total flight time: 3 hours and 55 minutes
  • Low-cost airline
  • 11 flights per week
  • Boeing 737-700 Passenger (Scimitar Winglets)
    Boeing 737-800 (winglets) Passenger/BBJ2
    Boeing 737MAX 8 Passenger
STL
Direct
SAN

The timetable & schedule information was updated at 2026-04-21

American Airlines

Via Phoenix with American Airlines

  • Total flight time: 4h 53m - 6h 09m.
  • One World Alliance
  • 113 flights per week
STL
 
Via PHX
 
SAN

The timetable & schedule information was updated at 2026-04-21

Southwest Airlines

Via Kansas City with Southwest Airlines

  • Total flight time: 5h 00m - 10h 30m.
  • Low-cost airline
  • 21 flights per week
  • Boeing 737-700 Passenger (Scimitar Winglets)
    Boeing 737-800 (winglets) Passenger/BBJ2
    Boeing 737MAX 8 Passenger
STL
 
Via MCI
 
SAN

The timetable & schedule information was updated at 2026-04-21

Southwest Airlines

Via Phoenix with Southwest Airlines

  • Total flight time: 5h 05m - 9h 30m.
  • Low-cost airline
  • 221 flights per week
  • Boeing 737-700 Passenger (Scimitar Winglets)
    Boeing 737-800 (winglets) Passenger/BBJ2
    Boeing 737MAX 8 Passenger
STL
 
Via PHX
 
SAN
 
Flight
Mon
Jun 15
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Jun 19
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Jun 20
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Jun 21
WN3967
WN3321
05:45
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05:45
05:45
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WN3967
WN2100
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06:10
06:10
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WN143
WN3323
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08:20
WN3968
WN5063
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09:45
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WN3968
WN3017
13:20
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13:20
13:20
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13:50
WN170
WN1202
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13:40
13:40
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WN4615
WN2475
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16:55
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WN4615
WN4052
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18:05
WN3306
WN1188
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18:20
18:20
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WN4615
WN3426
18:45
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18:45
18:45
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SHOW RETURN SCHEDULE
CHECK PRICES FOR STL - SAN

The timetable & schedule information was updated at 2026-04-21

Southwest Airlines

Via Las Vegas with Southwest Airlines

  • Total flight time: 5h 15m - 11h 15m.
  • Low-cost airline
  • 242 flights per week
  • Boeing 737-700 Passenger (Scimitar Winglets)
    Boeing 737-800 (winglets) Passenger/BBJ2
    Boeing 737MAX 8 Passenger
STL
 
Via LAS
 
SAN
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
WN3934
WN347
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05:30
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WN3934
WN2325
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05:35
05:35
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WN3934
WN1191
06:00
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06:00
06:00
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WN3678
WN1191
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06:35
WN143
WN4
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08:20
WN3369
WN2747
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08:40
WN2327
WN2272
09:15
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09:15
09:15
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WN4177
WN3620
09:55
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09:55
09:55
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WN4177
WN1096
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10:15
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WN1322
WN1288
14:15
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14:15
14:15
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WN4359
WN1288
14:20
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14:20
14:20
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WN5054
WN1288
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14:25
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WN240
WN1057
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14:40
WN4359
WN954
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15:05
15:05
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WN329
WN1227
15:20
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15:20
15:20
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WN4359
WN2330
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16:10
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WN5060
WN2330
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16:40
WN3935
WN2331
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18:55
18:55
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WN3935
WN294
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19:35
WN1761
WN1168
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19:35
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WN3935
WN2871
19:45
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19:45
19:45
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SHOW RETURN SCHEDULE
CHECK PRICES FOR STL - SAN

The timetable & schedule information was updated at 2026-04-21

Staying up-to-date with the airlines

At Airlineinformation.com you can learn all about the airlines operating around the world together with their destinations and where they operate. You will get a transparent overview of airlines with scheduled flights between any two destinations with non-stop or 1-stop flights regardless of price or availability.
Flight data on this page was last updated on 2026-06-02