Airlines with flights from Saint Louis to San Diego
There are five airlines with scheduled flights between STL and SAN. Southwest is the only airline with non-stop flights from Saint Louis Airport to San Diego International Airport and the flight time is 4 hours.
There are five airlines with scheduled flights between STL and SAN. Southwest is the only airline with non-stop flights from Saint Louis Airport to San Diego International Airport and the flight time is 4 hours. Choose airline
Direct
Non-stop
4h 0min
Via Phoenix
4h 53min
Via Kansas City
5h 0min
Via Phoenix
5h 5min
Via Las Vegas
5h 15min
Via Dallas
5h 15min
Via Denver
5h 20min
Via Dallas
5h 23min
Via Denver
5h 25min
Via Austin
5h 30min
Via Salt Lake City
5h 38min
Via Denver
5h 42min
Via Houston
5h 55min
Via Nashville
6h 0min
Via Chicago
6h 5min
Via Minneapolis
6h 5min
Via Chicago
6h 16min
Via Houston
6h 37min
Via Chicago
6h 38min
Via Las Vegas
6h 38min
Via San Antonio
6h 55min
Via Dallas
8h 23min
Via Omaha
5h 15min
Schedules
Non-stop with Southwest Airlines
-
Total flight time: 4 hours
-
Low-cost airline
-
9 flights per week
-
Boeing 737-800 (winglets) Passenger/BBJ2Boeing 737MAX 8 Passenger
STL
Direct
SAN
W32, Aug 03 - Aug 09
Flight
Mon
Aug 3
Tue
Aug 4
Wed
Aug 5
Thu
Aug 6
Fri
Aug 7
Sat
Aug 8
Sun
Aug 9
WN4283
08:10
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----
----
----
----
----
WN3886
----
08:25
08:25
08:35
08:35
----
08:25
WN3181
----
----
----
----
----
14:15
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The timetable & schedule information was updated at 2026-04-21
Via Phoenix with American Airlines
-
Total flight time: 4h 53m - 6h 09m.
-
One World Alliance
-
113 flights per week
STL
Via PHX
SAN
W32, Aug 03 - Aug 09
Flight
Mon
Aug 3
Tue
Aug 4
Wed
Aug 5
Thu
Aug 6
Fri
Aug 7
Sat
Aug 8
Sun
Aug 9
AA2574
AA2122
AA2122
----
----
08:00
08:00
08:00
08:00
08:00
AA2574
AA2477
AA2477
08:00
08:00
----
----
----
----
----
AA590
AA480
AA480
----
----
----
14:28
----
----
14:28
AA3179
AA2466
AA2466
14:38
14:38
----
----
----
----
----
The timetable & schedule information was updated at 2026-04-21
Via Kansas City with Southwest Airlines
-
Total flight time: 5h 00m - 10h 30m.
-
Low-cost airline
-
21 flights per week
-
Boeing 737-800 (winglets) Passenger/BBJ2Boeing 737MAX 8 Passenger
STL
Via MCI
SAN
W32, Aug 03 - Aug 09
Flight
Mon
Aug 3
Tue
Aug 4
Wed
Aug 5
Thu
Aug 6
Fri
Aug 7
Sat
Aug 8
Sun
Aug 9
WN3261
WN2533
WN2533
----
----
----
----
----
----
08:25
WN3261
WN254
WN254
----
----
----
----
----
10:10
----
WN3944
WN2580
WN2580
16:45
----
----
----
----
----
----
The timetable & schedule information was updated at 2026-04-21
Via Phoenix with Southwest Airlines
-
Total flight time: 5h 05m - 9h 30m.
-
Low-cost airline
-
221 flights per week
-
Boeing 737-800 (winglets) Passenger/BBJ2Boeing 737MAX 8 Passenger
STL
Via PHX
SAN
W32, Aug 03 - Aug 09
Flight
Mon
Aug 3
Tue
Aug 4
Wed
Aug 5
Thu
Aug 6
Fri
Aug 7
Sat
Aug 8
Sun
Aug 9
WN3967
WN3321
WN3321
05:45
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----
----
----
----
----
WN4593
WN548
WN548
----
----
----
06:00
06:00
----
----
WN4668
WN548
WN548
----
----
----
----
----
----
06:15
WN830
WN366
WN366
----
07:35
07:35
----
----
----
----
WN225
WN420
WN420
----
----
----
----
----
----
09:45
WN3877
WN3250
WN3250
----
----
----
----
----
11:50
----
WN3877
WN957
WN957
----
----
----
11:55
11:55
----
----
WN2838
WN3251
WN3251
----
11:55
11:55
----
----
----
----
WN3968
WN3017
WN3017
13:20
----
----
----
----
----
----
WN4593
WN2571
WN2571
----
----
----
----
----
14:15
----
WN2530
WN4372
WN4372
----
----
----
14:20
14:20
----
----
WN1337
WN4373
WN4373
----
17:00
17:00
----
----
----
----
WN4593
WN397
WN397
----
----
----
----
----
----
17:10
WN4380
WN4373
WN4373
----
----
----
18:00
18:00
----
----
WN4615
WN3426
WN3426
18:45
----
----
----
----
----
----
The timetable & schedule information was updated at 2026-04-21
Via Las Vegas with Southwest Airlines
-
Total flight time: 5h 15m - 11h 15m.
-
Low-cost airline
-
242 flights per week
-
Boeing 737-800 (winglets) Passenger/BBJ2Boeing 737MAX 8 Passenger
STL
Via LAS
SAN
W32, Aug 03 - Aug 09
Flight
Mon
Aug 3
Tue
Aug 4
Wed
Aug 5
Thu
Aug 6
Fri
Aug 7
Sat
Aug 8
Sun
Aug 9
WN3845
WN2266
WN2266
----
05:35
05:35
----
----
----
----
WN3845
WN554
WN554
----
----
----
----
----
----
05:50
WN3845
WN755
WN755
----
----
----
05:55
05:55
----
----
WN3934
WN1191
WN1191
06:00
----
----
----
----
----
----
WN3845
WN4926
WN4926
----
----
----
----
----
07:10
----
WN1003
WN2266
WN2266
----
----
----
08:25
08:25
----
----
WN2843
WN4139
WN4139
----
----
----
----
----
----
08:25
WN801
WN2269
WN2269
----
----
----
----
----
08:30
----
WN3063
WN471
WN471
----
----
----
----
----
08:30
----
WN471
WN2269
WN2269
----
----
----
----
----
09:00
----
WN2327
WN2272
WN2272
09:15
----
----
----
----
----
----
WN4177
WN3620
WN3620
09:55
----
----
----
----
----
----
WN3846
WN2269
WN2269
----
11:35
11:35
----
----
----
----
WN3846
WN2268
WN2268
----
----
----
----
----
12:20
14:35
WN3846
WN474
WN474
----
----
----
13:45
13:45
----
----
WN1322
WN1288
WN1288
14:15
----
----
----
----
----
----
WN4359
WN1288
WN1288
14:20
----
----
----
----
----
----
WN4187
WN4635
WN4635
----
----
----
----
----
14:25
----
WN329
WN1227
WN1227
15:20
----
----
----
----
----
----
WN3847
WN4635
WN4635
----
----
----
----
----
16:20
----
WN3847
WN369
WN369
----
17:25
17:25
----
----
----
WN3847
WN425
WN425
----
----
----
18:25
18:25
----
----
WN3847
WN138
WN138
----
----
----
----
----
----
18:40
WN3935
WN2871
WN2871
19:45
----
----
----
----
----
----
The timetable & schedule information was updated at 2026-04-21
Via Denver with United
Via Salt Lake City with Delta
Via Denver with Frontier