Airlines with flights from Saint Louis to San Diego
There are five airlines with scheduled flights between STL and SAN. Southwest is the only airline with non-stop flights from Saint Louis Airport to San Diego International Airport and the flight time is 3 hours and 55 minutes.
Choose airline
Schedules
Non-stop with Southwest Airlines
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Total flight time: 3 hours and 55 minutes
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Low-cost airline
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11 flights per week
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Boeing 737-700 Passenger (Scimitar Winglets)Boeing 737-800 (winglets) Passenger/BBJ2Boeing 737MAX 8 Passenger
STL
Direct
SAN
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
WN4283
08:10
08:30
08:30
08:10
08:10
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08:25
WN2526
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----
----
----
----
14:20
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WN2528
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----
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----
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20:50
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WN1959
----
----
----
----
----
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21:35
The timetable & schedule information was updated at 2026-04-21
Via Phoenix with American Airlines
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Total flight time: 4h 53m - 6h 09m.
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One World Alliance
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113 flights per week
STL
Via PHX
SAN
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
AA2574
AA2477
AA2477
08:00
08:00
08:00
08:00
08:00
08:00
08:00
AA3179
AA2466
AA2466
14:37
----
----
14:37
14:37
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14:37
The timetable & schedule information was updated at 2026-04-21
Via Kansas City with Southwest Airlines
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Total flight time: 5h 00m - 10h 30m.
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Low-cost airline
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21 flights per week
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Boeing 737-700 Passenger (Scimitar Winglets)Boeing 737-800 (winglets) Passenger/BBJ2Boeing 737MAX 8 Passenger
STL
Via MCI
SAN
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
WN3943
WN3389
WN3389
----
----
----
----
----
10:15
----
WN762
WN4457
WN4457
----
14:10
14:10
----
----
----
----
WN3944
WN2580
WN2580
16:45
----
----
16:45
16:45
----
----
The timetable & schedule information was updated at 2026-04-21
Via Phoenix with Southwest Airlines
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Total flight time: 5h 05m - 9h 30m.
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Low-cost airline
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221 flights per week
-
Boeing 737-700 Passenger (Scimitar Winglets)Boeing 737-800 (winglets) Passenger/BBJ2Boeing 737MAX 8 Passenger
STL
Via PHX
SAN
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
WN3967
WN3321
WN3321
05:45
----
----
05:45
05:45
----
----
WN3967
WN2100
WN2100
----
06:10
06:10
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----
----
----
WN143
WN3323
WN3323
----
----
----
----
----
----
08:20
WN3968
WN5063
WN5063
----
----
----
----
----
09:45
----
WN3968
WN3017
WN3017
13:20
----
----
13:20
13:20
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13:50
WN170
WN1202
WN1202
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13:40
13:40
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----
----
----
WN4615
WN2475
WN2475
----
----
----
----
----
16:55
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WN4615
WN4052
WN4052
----
----
----
----
----
----
18:05
WN3306
WN1188
WN1188
----
18:20
18:20
----
----
----
----
WN4615
WN3426
WN3426
18:45
----
----
18:45
18:45
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----
The timetable & schedule information was updated at 2026-04-21
Via Las Vegas with Southwest Airlines
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Total flight time: 5h 15m - 11h 15m.
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Low-cost airline
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242 flights per week
-
Boeing 737-700 Passenger (Scimitar Winglets)Boeing 737-800 (winglets) Passenger/BBJ2Boeing 737MAX 8 Passenger
STL
Via LAS
SAN
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
WN3934
WN347
WN347
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----
----
----
----
05:30
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WN3934
WN2325
WN2325
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05:35
05:35
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----
----
----
WN3934
WN1191
WN1191
06:00
----
----
06:00
06:00
----
----
WN3678
WN1191
WN1191
----
----
----
----
----
----
06:35
WN143
WN4
WN4
----
----
----
----
----
----
08:20
WN3369
WN2747
WN2747
----
----
----
----
----
----
08:40
WN2327
WN2272
WN2272
09:15
----
----
09:15
09:15
----
----
WN4177
WN3620
WN3620
09:55
----
----
09:55
09:55
----
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WN4177
WN1096
WN1096
----
----
----
----
----
10:15
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WN1322
WN1288
WN1288
14:15
----
----
14:15
14:15
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WN4359
WN1288
WN1288
14:20
----
----
14:20
14:20
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----
WN5054
WN1288
WN1288
----
----
----
----
----
14:25
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WN240
WN1057
WN1057
----
----
----
----
----
----
14:40
WN4359
WN954
WN954
----
15:05
15:05
----
----
----
----
WN329
WN1227
WN1227
15:20
----
----
15:20
15:20
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WN4359
WN2330
WN2330
----
----
----
----
----
16:10
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WN5060
WN2330
WN2330
----
----
----
----
----
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16:40
WN3935
WN2331
WN2331
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18:55
18:55
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----
----
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WN3935
WN294
WN294
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----
----
----
----
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19:35
WN1761
WN1168
WN1168
----
----
----
----
----
19:35
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WN3935
WN2871
WN2871
19:45
----
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19:45
19:45
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The timetable & schedule information was updated at 2026-04-21

There are five airlines with scheduled flights between STL and SAN. Southwest is the only airline with non-stop flights from Saint Louis Airport to San Diego International Airport and the flight time is 3 hours and 55 minutes.
Via Denver with United
Via Salt Lake City with Delta
Via Denver with Frontier