Airlines with flights from San Diego to Saint Louis
There are five airlines with scheduled flights between SAN and STL. Southwest is the only airline with non-stop flights from San Diego International Airport to Saint Louis Airport and the flight time is 3 hours and 30 minutes.
Choose airline
Schedules
Non-stop with Southwest Airlines
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Total flight time: 3 hours and 30 minutes
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Low-cost airline
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9 flights per week
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Boeing 737MAX 8 PassengerBoeing 737-700 Passenger (Scimitar Winglets)Boeing 737-800 (winglets) Passenger/BBJ2
SAN
Direct
STL
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
WN3760
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----
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----
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06:30
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WN2231
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----
----
----
----
----
06:35
WN2075
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07:05
07:05
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WN3552
13:30
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13:30
13:30
12:20
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WN3677
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13:20
The timetable & schedule information was updated at 2026-04-21
Via Phoenix with American Airlines
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Total flight time: 4h 52m - 5h 56m.
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One World Alliance
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72 flights per week
SAN
Via PHX
STL
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
AA625
AA3179
AA3179
06:25
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----
06:25
06:25
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06:25
AA2461
AA3179
AA3179
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09:50
09:50
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----
09:50
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AA2470
AA890
AA890
16:22
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16:22
16:22
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16:22
The timetable & schedule information was updated at 2026-04-21
Via Denver with Southwest Airlines
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Total flight time: 4h 55m - 10h 05m.
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Low-cost airline
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247 flights per week
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Boeing 737MAX 8 PassengerBoeing 737-700 Passenger (Scimitar Winglets)Boeing 737-800 (winglets) Passenger/BBJ2
SAN
Via DEN
STL
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
WN3493
WN3152
WN3152
06:30
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06:30
06:30
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----
WN3493
WN5066
WN5066
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----
----
----
----
06:35
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WN3370
WN3152
WN3152
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----
----
----
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06:40
WN3494
WN3152
WN3152
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07:45
07:45
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07:45
WN2763
WN3152
WN3152
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----
----
----
----
07:50
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WN3263
WN4213
WN4213
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08:40
08:40
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----
----
----
WN120
WN4213
WN4213
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08:45
08:45
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----
----
----
WN3494
WN64
WN64
09:20
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----
09:20
09:20
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----
WN3263
WN64
WN64
09:45
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----
09:45
09:45
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----
WN3495
WN64
WN64
10:35
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----
10:35
10:35
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----
WN3495
WN4213
WN4213
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10:55
10:55
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----
WN1133
WN1756
WN1756
12:10
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----
12:10
12:10
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----
WN3496
WN1718
WN1718
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----
----
----
----
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12:45
WN1222
WN1756
WN1756
12:55
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----
12:55
12:55
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WN3496
WN1756
WN1756
13:20
13:10
13:10
13:20
13:20
14:00
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WN3497
WN1758
WN1758
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----
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----
----
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14:50
WN3497
WN1756
WN1756
14:55
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----
14:55
14:55
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----
WN3497
WN1324
WN1324
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15:40
15:40
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----
----
----
The timetable & schedule information was updated at 2026-04-21
Via Phoenix with Southwest Airlines
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Total flight time: 4h 55m - 10h 00m.
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Low-cost airline
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214 flights per week
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Boeing 737MAX 8 PassengerBoeing 737-700 Passenger (Scimitar Winglets)Boeing 737-800 (winglets) Passenger/BBJ2
SAN
Via PHX
STL
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
WN425
WN174
WN174
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06:40
06:40
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WN248
WN174
WN174
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07:50
07:50
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----
----
----
WN3263
WN174
WN174
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08:40
08:40
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----
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----
WN3818
WN765
WN765
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----
----
----
----
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10:10
WN765
WN3353
WN3353
13:50
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----
13:50
13:50
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WN3525
WN878
WN878
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15:05
15:05
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----
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WN1682
WN3280
WN3280
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----
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15:40
WN3523
WN878
WN878
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16:25
16:25
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WN3300
WN1747
WN1747
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----
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16:50
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WN3076
WN3280
WN3280
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17:00
WN2521
WN3354
WN3354
17:10
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17:10
17:10
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WN4173
WN3354
WN3354
18:55
----
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18:55
18:55
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The timetable & schedule information was updated at 2026-04-21
Via Kansas City with Southwest Airlines
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Total flight time: 5h 00m - 6h 20m.
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Low-cost airline
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13 flights per week
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Boeing 737MAX 8 PassengerBoeing 737-700 Passenger (Scimitar Winglets)Boeing 737-800 (winglets) Passenger/BBJ2
SAN
Via MCI
STL
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
WN1788
WN2083
WN2083
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----
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06:35
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The timetable & schedule information was updated at 2026-04-21

There are five airlines with scheduled flights between SAN and STL. Southwest is the only airline with non-stop flights from San Diego International Airport to Saint Louis Airport and the flight time is 3 hours and 30 minutes.
Via Salt Lake City with Delta
Via Denver with United
Via Denver with Frontier