Airlines with flights from Chicago to Greenville
There are four airlines with scheduled flights between ORD and GSP. Both American Airlines and United operates non-stop flights from Chicago O'Hare to Greenville-Spartanburg International and the flight time is 2 hours and 1 minutes.
There are four airlines with scheduled flights between ORD and GSP. Both American Airlines and United operates non-stop flights from Chicago O'Hare to Greenville-Spartanburg International and the flight time is 2 hours and 1 minutes. Choose airline
Direct
Non-stop
2h 1min
Direct
Non-stop
2h 5min
Via Charlotte
3h 38min
Via Atlanta
3h 43min
Via Washington
3h 44min
Via Detroit
3h 55min
Via Dulles
4h 15min
Via Nashville
5h 45min
Schedules
Non-stop with American Airlines
-
Total flight time: 2 hours and 1 minutes
-
One World Alliance
-
Chicago is a American Airlines hub.
-
29 flights per week
-
Embraer 175
-
First class available
ORD
Direct
GSP
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
AA3556
08:00
08:00
08:00
08:00
08:00
08:08
08:00
AA3559
15:07
15:07
15:07
15:07
15:07
15:08
15:07
AA3492
20:49
20:49
20:49
20:49
20:49
20:59
20:49
The timetable & schedule information was updated at 2026-04-21
Non-stop with United Airlines
-
Total flight time: 2 hours and 5 minutes
-
Chicago is a United Airlines hub (Largest hub ).
-
20 flights per week
-
Canadair (Bombardier) Regional Jet 550Embraer 175 (Enhanced Winglets)
-
First class available
ORD
Direct
GSP
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
UA4531
06:55
----
06:55
06:55
06:55
06:55
06:55
UA5403
13:55
13:55
13:55
13:55
13:55
13:55
13:55
UA4794
18:10
18:10
18:10
18:10
18:10
18:10
18:10
The timetable & schedule information was updated at 2026-04-21
Via Charlotte with American Airlines
-
Total flight time: 3h 38m - 6h 08m.
-
One World Alliance
-
Chicago is a American Airlines hub.
-
227 flights per week
-
Embraer 175
ORD
Via CLT
GSP
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
AA2842
AA5799
AA5799
05:10
05:10
05:10
05:10
05:10
05:00
05:10
AA1784
AA5802
AA5802
06:55
06:55
06:55
06:55
06:55
----
06:55
AA3222
AA5805
AA5805
07:58
07:58
07:58
07:58
07:58
07:58
07:58
AA2502
AA5805
AA5805
08:48
08:48
08:48
08:48
08:48
08:48
08:48
AA2681
AA5203
AA5203
11:55
11:55
11:55
11:55
11:55
12:33
11:55
AA3280
AA3422
AA3422
13:19
----
----
13:19
13:19
13:19
13:19
AA3280
AA5870
AA5870
----
13:19
13:19
----
----
----
----
AA1683
AA5524
AA5524
16:45
16:45
16:45
16:45
16:45
16:45
16:45
AA2695
AA5504
AA5504
17:34
17:34
17:34
17:34
17:34
17:34
17:34
AA689
AA5504
AA5504
18:47
18:47
18:47
18:47
18:47
18:47
18:47
The timetable & schedule information was updated at 2026-04-21
Via Atlanta with Delta Air Lines
-
Total flight time: 3h 43m - 6h 01m.
-
Sky Team Alliance
-
197 flights per week
ORD
Via ATL
GSP
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
DL1264
DL2158
DL2158
05:30
05:30
05:30
05:30
05:30
----
05:30
DL1264
DL1725
DL1725
----
----
----
----
----
05:30
----
DL1247
DL1725
DL1725
06:40
06:40
06:40
06:40
06:40
06:40
06:40
DL2426
DL1273
DL1273
08:03
08:03
08:03
08:03
08:03
----
08:03
DL1178
DL1273
DL1273
----
----
----
----
----
09:48
----
DL1178
DL3095
DL3095
09:48
09:48
09:48
09:48
09:48
----
09:48
DL1147
DL3095
DL3095
11:23
11:23
11:23
11:23
11:23
11:23
11:23
DL2894
DL1021
DL1021
13:46
13:46
13:46
13:46
13:46
13:49
13:46
DL1477
DL2319
DL2319
15:22
15:22
15:22
15:22
15:22
15:25
----
DL1477
DL3136
DL3136
----
----
----
----
----
----
15:39
DL2740
DL2281
DL2281
17:40
17:40
17:40
17:40
17:40
----
17:40
DL2738
DL2281
DL2281
----
----
----
----
----
18:10
----
The timetable & schedule information was updated at 2026-04-21
Via Washington with American Airlines
-
Total flight time: 3h 44m - 6h 50m.
-
One World Alliance
-
Chicago is a American Airlines hub.
-
67 flights per week
-
Embraer 175
ORD
Via DCA
GSP
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
AA4552
AA5204
AA5204
----
----
----
----
----
----
06:00
AA4339
AA5204
AA5204
06:00
06:00
06:00
06:00
06:00
----
----
AA2965
AA5204
AA5204
----
----
----
----
07:10
----
07:10
AA2398
AA5208
AA5208
----
----
----
----
----
09:52
----
AA4360
AA5208
AA5208
10:41
10:41
10:41
10:41
10:41
----
----
AA4789
AA5208
AA5208
----
----
----
----
----
10:42
----
AA2769
AA5497
AA5497
14:57
14:57
14:57
14:57
14:57
----
14:57
The timetable & schedule information was updated at 2026-04-21
Via Detroit with Delta Air Lines
-
Total flight time: 3h 55m - 6h 16m.
-
Sky Team Alliance
-
35 flights per week
ORD
Via DTW
GSP
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
DL3673
DL5090
DL5090
11:30
11:30
11:30
11:30
11:30
----
11:30
DL5816
DL1561
DL1561
----
----
----
----
----
14:35
----
The timetable & schedule information was updated at 2026-04-21
Via Nashville with Southwest