Airlines with flights from Chicago to Des Moines
There are three airlines with scheduled flights between ORD and DSM. Both American Airlines and United operates non-stop flights from Chicago O'Hare to Des Moines International and the flight time is 1 hour and 33 minutes. You can also connect with Delta via Minneapolis with a flight time of 3 hours and 22 minutes.
Choose airline
Schedules
Non-stop with American Airlines
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Total flight time: 1 hour and 33 minutes
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One World Alliance
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Chicago is a American Airlines hub.
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37 flights per week
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Canadair (Bombardier) Regional Jet 700 and Challenger 870Embraer 175Embraer 170
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First class available
ORD
Direct
DSM
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
AA4969
07:00
07:00
07:00
07:00
07:00
07:00
07:00
AA4676
11:45
11:45
11:45
11:45
11:45
11:41
11:41
AA4973
17:00
17:00
17:00
17:00
17:00
16:23
17:00
AA4102
18:00
18:00
18:00
18:00
18:00
18:00
18:00
AA4442
23:00
23:00
23:00
23:00
23:00
22:30
23:00
The timetable & schedule information was updated at 2026-04-21
Non-stop with United Airlines
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Total flight time: 1 hour and 31 minutes
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Chicago is a United Airlines hub (Largest hub ).
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36 flights per week
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Airbus A319Canadair (Bombardier) Regional Jet 550Embraer 175 (Enhanced Winglets)Airbus A320
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Business and first class available
ORD
Direct
DSM
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
UA581
08:55
08:55
08:55
08:55
08:50
08:55
08:55
UA4605
12:41
12:41
12:41
12:41
12:41
12:41
12:41
UA5409
16:36
----
16:36
16:36
16:36
16:36
----
UA4522
----
16:42
----
----
----
----
16:42
UA5990
17:50
17:50
17:50
17:50
17:50
17:50
17:50
UA2808
21:20
21:20
21:20
21:20
21:20
21:20
21:20
The timetable & schedule information was updated at 2026-04-21
Via Minneapolis with Delta Air Lines
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Total flight time: 3h 22m - 5h 37m.
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Sky Team Alliance
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55 flights per week
ORD
Via MSP
DSM
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
DL1717
DL4998
DL4998
06:30
06:30
06:30
06:30
06:30
06:30
06:30
DL1554
DL5490
DL5490
08:36
08:36
08:36
08:36
08:36
----
----
DL1567
DL4913
DL4913
12:27
12:27
12:27
12:27
12:27
----
12:27
DL4767
DL4913
DL4913
----
----
----
----
----
12:46
----
DL1533
DL5253
DL5253
15:55
15:55
15:55
15:55
15:55
15:55
15:55
The timetable & schedule information was updated at 2026-04-21

There are three airlines with scheduled flights between ORD and DSM. Both American Airlines and United operates non-stop flights from Chicago O'Hare to Des Moines International and the flight time is 1 hour and 33 minutes. You can also connect with Delta via Minneapolis with a flight time of 3 hours and 22 minutes.