Airlines with flights from Chicago to Des Moines

There are three airlines with scheduled flights between ORD and DSM. Both American Airlines and United operates non-stop flights from Chicago O'Hare to Des Moines International and the flight time is 1 hour and 33 minutes. You can also connect with Delta via Minneapolis with a flight time of 3 hours and 22 minutes.

Choose airline

Schedules

American Airlines

Non-stop with American Airlines

  • Total flight time: 1 hour and 33 minutes
  • One World Alliance
  • Chicago is a American Airlines hub.
  • 37 flights per week
  • Canadair (Bombardier) Regional Jet 700 and Challenger 870
    Embraer 175
    Embraer 170
  • First class available
ORD
Direct
DSM
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
AA4969
07:00
07:00
07:00
07:00
07:00
07:00
07:00
AA4676
11:45
11:45
11:45
11:45
11:45
11:41
11:41
AA4973
17:00
17:00
17:00
17:00
17:00
16:23
17:00
AA4102
18:00
18:00
18:00
18:00
18:00
18:00
18:00
AA4442
23:00
23:00
23:00
23:00
23:00
22:30
23:00
SHOW RETURN SCHEDULE
CHECK PRICES FOR ORD - DSM

The timetable & schedule information was updated at 2026-04-21

United Airlines

Non-stop with United Airlines

  • Total flight time: 1 hour and 31 minutes
  • Chicago is a United Airlines hub (Largest hub ).
  • 36 flights per week
  • Airbus A319
    Canadair (Bombardier) Regional Jet 550
    Embraer 175 (Enhanced Winglets)
    Airbus A320
  • Business and first class available
ORD
Direct
DSM
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
UA581
08:55
08:55
08:55
08:55
08:50
08:55
08:55
UA4605
12:41
12:41
12:41
12:41
12:41
12:41
12:41
UA5409
16:36
----
16:36
16:36
16:36
16:36
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UA4522
----
16:42
----
----
----
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16:42
UA5990
17:50
17:50
17:50
17:50
17:50
17:50
17:50
UA2808
21:20
21:20
21:20
21:20
21:20
21:20
21:20
SHOW RETURN SCHEDULE
CHECK PRICES FOR ORD - DSM

The timetable & schedule information was updated at 2026-04-21

Delta Air Lines

Via Minneapolis with Delta Air Lines

  • Total flight time: 3h 22m - 5h 37m.
  • Sky Team Alliance
  • 55 flights per week
ORD
 
Via MSP
 
DSM
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
DL1717
DL4998
06:30
06:30
06:30
06:30
06:30
06:30
06:30
DL1554
DL5490
08:36
08:36
08:36
08:36
08:36
----
----
DL1567
DL4913
12:27
12:27
12:27
12:27
12:27
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12:27
DL4767
DL4913
----
----
----
----
----
12:46
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DL1533
DL5253
15:55
15:55
15:55
15:55
15:55
15:55
15:55
SHOW RETURN SCHEDULE
CHECK PRICES FOR ORD - DSM

The timetable & schedule information was updated at 2026-04-21

Staying up-to-date with the airlines

At Airlineinformation.com you can learn all about the airlines operating around the world together with their destinations and where they operate. You will get a transparent overview of airlines with scheduled flights between any two destinations with non-stop or 1-stop flights regardless of price or availability.
Flight data on this page was last updated on 2026-06-02