Airlines with flights from Des Moines to Chicago

There are three airlines with scheduled flights between DSM and ORD. Both American Airlines and United operates non-stop flights from Des Moines International to Chicago O'Hare and the flight time is 1 hour and 43 minutes. You can also connect with Delta via Minneapolis with a flight time of 3 hours and 25 minutes.

Choose airline

Schedules

American Airlines

Non-stop with American Airlines

  • Total flight time: 1 hour and 43 minutes
  • One World Alliance
  • Chicago is a American Airlines hub.
  • 41 flights per week
  • Embraer 175
    Canadair (Bombardier) Regional Jet 700 and Challenger 870
    Embraer 170
  • First class available
DSM
Direct
ORD
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
AA4519
05:00
05:00
05:00
05:00
05:00
05:00
05:00
AA4969
09:23
09:23
09:23
09:23
09:23
09:18
09:03
AA4676
13:51
13:51
13:51
13:51
13:51
13:47
13:47
AA4973
19:09
19:09
19:09
19:09
19:09
18:32
19:09
AA4102
20:05
20:05
20:05
20:05
20:05
20:05
20:05
SHOW RETURN SCHEDULE
CHECK PRICES FOR DSM - ORD

The timetable & schedule information was updated at 2026-04-21

United Airlines

Non-stop with United Airlines

  • Total flight time: 1 hour and 39 minutes
  • Chicago is a United Airlines hub (Largest hub ).
  • 35 flights per week
  • Airbus A319
    Boeing 737-900 Passenger
    Embraer 175 (Enhanced Winglets)
    Canadair (Bombardier) Regional Jet 550
  • Business and first class available
DSM
Direct
ORD
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
UA1856
06:00
06:00
06:00
06:00
06:00
06:00
06:00
UA5318
08:00
08:00
08:00
08:00
08:00
08:00
08:00
UA1410
11:26
11:26
11:26
11:26
11:21
11:26
11:26
UA4397
14:49
14:49
14:49
14:49
14:49
14:49
14:49
UA6050
18:50
----
18:50
18:50
18:50
18:50
----
UA4178
----
18:50
----
----
----
----
18:50
SHOW RETURN SCHEDULE
CHECK PRICES FOR DSM - ORD

The timetable & schedule information was updated at 2026-04-21

Delta Air Lines

Via Minneapolis with Delta Air Lines

  • Total flight time: 3h 25m - 5h 19m.
  • Sky Team Alliance
  • 96 flights per week
DSM
 
Via MSP
 
ORD
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
DL5402
DL1567
06:43
06:43
06:43
06:43
06:43
----
06:43
DL5402
DL4767
----
----
----
----
----
06:43
----
DL4998
DL1533
10:54
10:54
10:54
10:54
10:54
10:54
10:54
DL5490
DL2130
14:45
14:45
14:45
14:45
14:45
----
14:45
DL5020
DL1563
18:03
18:03
18:03
18:03
18:03
18:03
18:03
SHOW RETURN SCHEDULE
CHECK PRICES FOR DSM - ORD

The timetable & schedule information was updated at 2026-04-21

Staying up-to-date with the airlines

At Airlineinformation.com you can learn all about the airlines operating around the world together with their destinations and where they operate. You will get a transparent overview of airlines with scheduled flights between any two destinations with non-stop or 1-stop flights regardless of price or availability.
Flight data on this page was last updated on 2026-05-25