Airlines with flights from Des Moines to Chicago
There are three airlines with scheduled flights between DSM and ORD. Both American Airlines and United operates non-stop flights from Des Moines International to Chicago O'Hare and the flight time is 1 hour and 43 minutes. You can also connect with Delta via Minneapolis with a flight time of 3 hours and 25 minutes.
Choose airline
Schedules
Non-stop with American Airlines
-
Total flight time: 1 hour and 43 minutes
-
One World Alliance
-
Chicago is a American Airlines hub.
-
41 flights per week
-
Embraer 175Canadair (Bombardier) Regional Jet 700 and Challenger 870Embraer 170
-
First class available
DSM
Direct
ORD
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
AA4519
05:00
05:00
05:00
05:00
05:00
05:00
05:00
AA4969
09:23
09:23
09:23
09:23
09:23
09:18
09:03
AA4676
13:51
13:51
13:51
13:51
13:51
13:47
13:47
AA4973
19:09
19:09
19:09
19:09
19:09
18:32
19:09
AA4102
20:05
20:05
20:05
20:05
20:05
20:05
20:05
The timetable & schedule information was updated at 2026-04-21
Non-stop with United Airlines
-
Total flight time: 1 hour and 39 minutes
-
Chicago is a United Airlines hub (Largest hub ).
-
35 flights per week
-
Airbus A319Boeing 737-900 PassengerEmbraer 175 (Enhanced Winglets)Canadair (Bombardier) Regional Jet 550
-
Business and first class available
DSM
Direct
ORD
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
UA1856
06:00
06:00
06:00
06:00
06:00
06:00
06:00
UA5318
08:00
08:00
08:00
08:00
08:00
08:00
08:00
UA1410
11:26
11:26
11:26
11:26
11:21
11:26
11:26
UA4397
14:49
14:49
14:49
14:49
14:49
14:49
14:49
UA6050
18:50
----
18:50
18:50
18:50
18:50
----
UA4178
----
18:50
----
----
----
----
18:50
The timetable & schedule information was updated at 2026-04-21
Via Minneapolis with Delta Air Lines
-
Total flight time: 3h 25m - 5h 19m.
-
Sky Team Alliance
-
96 flights per week
DSM
Via MSP
ORD
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
DL5402
DL1567
DL1567
06:43
06:43
06:43
06:43
06:43
----
06:43
DL5402
DL4767
DL4767
----
----
----
----
----
06:43
----
DL4998
DL1533
DL1533
10:54
10:54
10:54
10:54
10:54
10:54
10:54
DL5490
DL2130
DL2130
14:45
14:45
14:45
14:45
14:45
----
14:45
DL5020
DL1563
DL1563
18:03
18:03
18:03
18:03
18:03
18:03
18:03
The timetable & schedule information was updated at 2026-04-21

There are three airlines with scheduled flights between DSM and ORD. Both American Airlines and United operates non-stop flights from Des Moines International to Chicago O'Hare and the flight time is 1 hour and 43 minutes. You can also connect with Delta via Minneapolis with a flight time of 3 hours and 25 minutes.