Airlines with flights from Chicago to Knoxville

There are three airlines with scheduled flights between MDW and TYS. Allegiant is the only airline with non-stop flights from Midway International Airport to Mc Ghee Tyson and the flight time is 1 hour and 27 minutes.

Choose airline

Schedules

Allegiant Air

Non-stop with Allegiant Air

  • Total flight time: 1 hour and 27 minutes
  • Low-cost airline
  • Knoxville is a Allegiant Air focus city (Operating base).
  • 2 flights per week
  • Airbus A320
MDW
Direct
TYS

The timetable & schedule information was updated at 2026-04-21

Southwest Airlines

Via Nashville with Southwest Airlines

  • Total flight time: 3h 05m - 6h 40m.
  • Low-cost airline
  • Chicago is a Southwest Airlines focus city (Operating base).
  • 43 flights per week
MDW
 
Via BNA
 
TYS
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
WN3855
WN4206
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06:10
WN1053
WN790
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06:40
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WN2959
WN4206
07:15
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07:15
07:15
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WN1337
WN4206
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07:55
WN3869
WN694
17:05
15:10
15:10
17:05
17:05
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WN1257
WN694
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15:30
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WN3614
WN432
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16:40
SHOW RETURN SCHEDULE
CHECK PRICES FOR MDW - TYS

The timetable & schedule information was updated at 2026-04-21

Delta Air Lines

Via Detroit with Delta Air Lines

  • Total flight time: 3h 27m - 5h 02m.
  • Sky Team Alliance
  • 7 flights per week
MDW
 
Via DTW
 
TYS

The timetable & schedule information was updated at 2026-04-21

Delta Air Lines

Via Atlanta with Delta Air Lines

  • Total flight time: 3h 30m - 5h 53m.
  • Sky Team Alliance
  • 121 flights per week
MDW
 
Via ATL
 
TYS
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
DL1285
DL1743
06:05
06:05
06:05
06:05
06:05
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06:05
DL1285
DL4724
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06:05
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DL1063
DL4641
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10:55
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DL1063
DL2571
11:05
11:05
11:05
11:05
11:05
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11:05
DL2417
DL3042
12:45
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12:45
12:45
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12:45
DL2417
DL5416
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12:45
12:45
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DL1728
DL2081
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17:11
17:11
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DL1728
DL3072
17:11
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17:11
17:11
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17:11
SHOW RETURN SCHEDULE
CHECK PRICES FOR MDW - TYS

The timetable & schedule information was updated at 2026-04-21

Southwest Airlines

Via Saint Louis with Southwest Airlines

  • Total flight time: 5h 25m - 5h 25m.
  • Low-cost airline
  • Chicago is a Southwest Airlines focus city (Operating base).
  • 3 flights per week
MDW
 
Via STL
 
TYS

The timetable & schedule information was updated at 2026-04-21

Staying up-to-date with the airlines

At Airlineinformation.com you can learn all about the airlines operating around the world together with their destinations and where they operate. You will get a transparent overview of airlines with scheduled flights between any two destinations with non-stop or 1-stop flights regardless of price or availability.
Flight data on this page was last updated on 2026-06-02