Airlines with flights from Los Angeles to Des Moines
There are five airlines with scheduled flights between LAX and DSM. American Airlines is the only airline with non-stop flights from LAX to Des Moines International and the flight time is 3 hours and 38 minutes.
Choose airline
Schedules
Non-stop with American Airlines
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Total flight time: 3 hours and 38 minutes
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One World Alliance
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Los Angeles is a American Airlines hub.
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7 flights per week
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Embraer 175
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First class available
LAX
Direct
DSM
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
AA4971
12:39
12:39
12:39
12:39
12:39
12:39
12:39
The timetable & schedule information was updated at 2026-04-21
Via Denver with Southwest Airlines
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Total flight time: 4h 40m - 8h 10m.
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Low-cost airline
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Los Angeles is a Southwest Airlines focus city (Operating base ).
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69 flights per week
LAX
Via DEN
DSM
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
WN2943
WN1524
WN1524
05:55
06:00
06:00
05:55
05:55
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WN735
WN1524
WN1524
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06:25
06:25
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----
----
----
WN2222
WN1524
WN1524
----
----
----
----
----
07:55
----
WN1591
WN1524
WN1524
----
07:55
07:55
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----
----
----
WN407
WN1524
WN1524
----
----
----
----
----
----
08:35
WN2975
WN2687
WN2687
----
----
----
----
----
----
12:20
WN2975
WN2940
WN2940
13:00
----
----
13:00
13:00
----
----
WN1599
WN2940
WN2940
13:05
----
----
13:05
13:05
----
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WN2392
WN2940
WN2940
14:55
13:15
13:15
14:55
14:55
14:20
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WN2392
WN2687
WN2687
----
----
----
----
----
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14:45
The timetable & schedule information was updated at 2026-04-21
Via Phoenix with American Airlines
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Total flight time: 4h 53m - 5h 55m.
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One World Alliance
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Los Angeles is a American Airlines hub.
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71 flights per week
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Embraer 175
LAX
Via PHX
DSM
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
AA2027
AA2516
AA2516
06:15
06:15
06:15
06:15
06:15
06:15
06:15
AA2032
AA568
AA568
16:40
16:40
16:40
16:40
16:40
16:40
16:40
The timetable & schedule information was updated at 2026-04-21
Via Denver with Frontier Airlines
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Total flight time: 4h 54m - 5h 01m.
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Low-cost airline
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1 flights per week
LAX
Via DEN
DSM
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
F93156
F91678
F91678
06:30
----
06:30
----
06:30
----
----
The timetable & schedule information was updated at 2026-04-21
Via Las Vegas with Southwest Airlines
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Total flight time: 5h 00m - 7h 00m.
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Low-cost airline
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Los Angeles is a Southwest Airlines focus city (Operating base ).
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41 flights per week
LAX
Via LAS
DSM
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
WN739
WN1755
WN1755
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----
----
----
----
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08:35
WN1326
WN1755
WN1755
----
----
----
----
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09:10
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WN1840
WN1755
WN1755
----
----
----
----
----
----
09:55
WN550
WN1755
WN1755
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10:25
10:25
----
----
----
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The timetable & schedule information was updated at 2026-04-21

There are five airlines with scheduled flights between LAX and DSM. American Airlines is the only airline with non-stop flights from LAX to Des Moines International and the flight time is 3 hours and 38 minutes.
Via Denver with United
Via Minneapolis with Delta