Airlines with flights from Des Moines to Los Angeles
There are five airlines with scheduled flights between DSM and LAX. American Airlines is the only airline with non-stop flights from Des Moines International to LAX and the flight time is 3 hours and 58 minutes.
Choose airline
Schedules
Non-stop with American Airlines
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Total flight time: 3 hours and 58 minutes
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One World Alliance
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Los Angeles is a American Airlines hub.
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7 flights per week
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Embraer 175
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First class available
DSM
Direct
LAX
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
AA4971
18:47
18:47
18:47
18:47
18:47
18:47
18:47
The timetable & schedule information was updated at 2026-04-21
Via Phoenix with American Airlines
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Total flight time: 4h 57m - 6h 30m.
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One World Alliance
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Los Angeles is a American Airlines hub.
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84 flights per week
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Embraer 175
DSM
Via PHX
LAX
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
AA1795
AA1668
AA1668
05:45
05:45
05:45
05:45
05:45
05:45
05:45
AA2516
AA6304
AA6304
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----
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14:24
AA2516
AA2930
AA2930
14:24
14:24
14:24
14:24
14:24
14:24
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The timetable & schedule information was updated at 2026-04-21
Via Denver with Southwest Airlines
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Total flight time: 5h 05m - 8h 45m.
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Low-cost airline
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Los Angeles is a Southwest Airlines focus city (Operating base ).
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42 flights per week
DSM
Via DEN
LAX
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
WN1769
WN1568
WN1568
06:10
06:25
06:25
06:10
06:10
06:10
06:10
WN1124
WN3110
WN3110
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18:10
WN2288
WN3110
WN3110
----
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----
----
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18:55
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WN1334
WN3110
WN3110
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19:00
19:00
----
----
----
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The timetable & schedule information was updated at 2026-04-21
Via Las Vegas with Southwest Airlines
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Total flight time: 5h 10m - 7h 25m.
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Low-cost airline
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Los Angeles is a Southwest Airlines focus city (Operating base ).
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25 flights per week
DSM
Via LAS
LAX
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
WN1771
WN4143
WN4143
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----
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12:05
WN1771
WN255
WN255
12:05
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12:05
12:05
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The timetable & schedule information was updated at 2026-04-21
Via Denver with United Airlines
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Total flight time: 5h 18m - 7h 48m.
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Los Angeles is a United Airlines hub (Secondary hub).
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136 flights per week
DSM
Via DEN
LAX
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
UA4777
UA1638
UA1638
05:50
05:50
05:50
05:50
05:50
05:50
05:50
UA1521
UA1013
UA1013
09:14
09:14
09:14
09:14
09:14
09:14
09:14
UA5288
UA774
UA774
11:34
11:34
11:34
11:34
11:34
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11:34
UA2764
UA1195
UA1195
13:35
13:35
13:35
13:35
13:35
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13:35
UA5277
UA1195
UA1195
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----
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13:40
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UA1781
UA2791
UA2791
17:17
17:17
17:17
17:17
17:17
17:17
17:17
The timetable & schedule information was updated at 2026-04-21

There are five airlines with scheduled flights between DSM and LAX. American Airlines is the only airline with non-stop flights from Des Moines International to LAX and the flight time is 3 hours and 58 minutes.
Via Denver with Frontier
Via Minneapolis with Delta