Airlines with flights from Istanbul to Madrid
There are 10 airlines with scheduled flights between IST and MAD. Both Turkish Airlines and Air Europa operates non-stop flights from Istanbul Airport to Barajas and the flight time is 4 hours and 30 minutes.
Choose airline
Schedules
Non-stop with Turkish Airlines
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Total flight time: 4 hours and 30 minutes
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Istanbul is a Turkish Airlines hub.
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23 flights per week
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Airbus A330-300Airbus A330-200Airbus A321neoBoeing 737-800 (winglets) Passenger/BBJ2Boeing 737MAX 8 Passenger
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Business class available
Flight
The timetable & schedule information was updated at 2026-04-21
Non-stop with Air Europa
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Total flight time: 4 hours and 15 minutes
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Sky Team Alliance
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Madrid is a Air Europa hub.
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7 flights per week
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Boeing 787-8
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Business class available
Flight
The timetable & schedule information was updated at 2026-04-21
Via Tunis with Tunisair
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Total flight time: 6h 45m - 6h 50m.
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6 flights per week
Flight
TU606
The timetable & schedule information was updated at 2026-04-21
Via Frankfurt with Lufthansa
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Total flight time: 7h 30m - 10h 45m.
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27 flights per week
Flight
LH1112
LH1122
The timetable & schedule information was updated at 2026-04-21
Via Athens with Aegean Airlines
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Total flight time: 7h 50m - 9h 50m.
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30 flights per week
Flight
A3702
The timetable & schedule information was updated at 2026-04-21
Via Paris with Air France
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Total flight time: 7h 55m - 8h 00m.
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Sky Team Alliance
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15 flights per week
Flight
AF1300
The timetable & schedule information was updated at 2026-04-21

There are 10 airlines with scheduled flights between IST and MAD. Both Turkish Airlines and Air Europa operates non-stop flights from Istanbul Airport to Barajas and the flight time is 4 hours and 30 minutes.
Via Krakow with LOT
Via Belgrade with Air Serbia
Via Algiers with Air Algerie
Via Malta with KM Malta Airlines