Airlines with flights from Des Moines to Phoenix

There are five airlines with scheduled flights between DSM and PHX. Both American Airlines and Southwest operates non-stop flights from Des Moines International to Phoenix Sky Harbor International and the flight time is 3 hours and 5 minutes.

Choose airline

Schedules

American Airlines

Non-stop with American Airlines

  • Total flight time: 3 hours and 5 minutes
  • One World Alliance
  • Phoenix is a American Airlines hub.
  • 15 flights per week
  • Airbus A319
    Airbus A320
  • First class available
DSM
Direct
PHX

The timetable & schedule information was updated at 2026-04-21

Southwest Airlines

Non-stop with Southwest Airlines

  • Total flight time: 3 hours
  • Low-cost airline
  • Phoenix is a Southwest Airlines focus city (Operating base ).
  • 4 flights per week
DSM
Direct
PHX

The timetable & schedule information was updated at 2026-04-21

Southwest Airlines

Via Denver with Southwest Airlines

  • Total flight time: 4h 30m - 8h 40m.
  • Low-cost airline
  • Phoenix is a Southwest Airlines focus city (Operating base ).
  • 45 flights per week
DSM
 
Via DEN
 
PHX
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
WN1769
WN1201
06:10
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06:10
06:10
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WN1769
WN3336
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06:10
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WN1769
WN1653
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06:10
WN1769
WN431
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06:25
06:25
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WN1770
WN1682
13:30
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13:30
13:30
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WN1124
WN1684
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18:10
WN2288
WN1684
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18:55
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WN1334
WN1684
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19:00
19:00
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SHOW RETURN SCHEDULE
CHECK PRICES FOR DSM - PHX

The timetable & schedule information was updated at 2026-04-21

United Airlines

Via Denver with United Airlines

  • Total flight time: 4h 49m - 7h 13m.
  • 129 flights per week
DSM
 
Via DEN
 
PHX
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
UA4777
UA1481
05:50
05:50
05:50
05:50
05:50
05:50
05:50
UA1521
UA1686
09:14
09:14
09:14
09:14
09:14
09:14
09:14
UA5288
UA1254
11:34
11:34
11:34
11:34
11:34
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11:34
UA2764
UA1254
13:35
13:35
13:35
13:35
13:35
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13:35
UA5277
UA1254
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13:40
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UA1781
UA1729
17:17
17:17
17:17
17:17
17:17
17:17
17:17
SHOW RETURN SCHEDULE
CHECK PRICES FOR DSM - PHX

The timetable & schedule information was updated at 2026-04-21

Southwest Airlines

Via Las Vegas with Southwest Airlines

  • Total flight time: 5h 10m - 7h 20m.
  • Low-cost airline
  • Phoenix is a Southwest Airlines focus city (Operating base ).
  • 27 flights per week
DSM
 
Via LAS
 
PHX

The timetable & schedule information was updated at 2026-04-21

American Airlines

Via Dallas with American Airlines

  • Total flight time: 5h 19m - 7h 38m.
  • One World Alliance
  • Phoenix is a American Airlines hub.
  • 118 flights per week
  • Airbus A319
    Airbus A320
DSM
 
Via DFW
 
PHX
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
AA2326
AA520
05:30
05:30
05:30
05:30
05:30
05:30
05:30
AA3495
AA1685
09:41
09:41
09:41
09:41
09:41
09:41
09:41
AA2421
AA1133
16:48
16:48
16:48
16:48
16:50
16:48
16:50
AA1762
AA3239
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19:02
19:02
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AA1762
AA2319
19:02
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19:02
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19:02
19:02
AA3934
AA2319
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19:07
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SHOW RETURN SCHEDULE
CHECK PRICES FOR DSM - PHX

The timetable & schedule information was updated at 2026-04-21

Staying up-to-date with the airlines

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Flight data on this page was last updated on 2026-06-02