Airlines with flights from Des Moines to Phoenix
There are five airlines with scheduled flights between DSM and PHX. Both American Airlines and Southwest operates non-stop flights from Des Moines International to Phoenix Sky Harbor International and the flight time is 3 hours and 5 minutes.
Choose airline
Schedules
Non-stop with American Airlines
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Total flight time: 3 hours and 5 minutes
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One World Alliance
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Phoenix is a American Airlines hub.
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15 flights per week
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Airbus A319Airbus A320
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First class available
Flight
The timetable & schedule information was updated at 2026-04-21
Non-stop with Southwest Airlines
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Total flight time: 3 hours
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Low-cost airline
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Phoenix is a Southwest Airlines focus city (Operating base ).
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4 flights per week
Flight
The timetable & schedule information was updated at 2026-04-21
Via Denver with Southwest Airlines
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Total flight time: 4h 30m - 8h 40m.
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Low-cost airline
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Phoenix is a Southwest Airlines focus city (Operating base ).
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45 flights per week
Flight
WN1201
WN3336
WN1653
WN431
WN1682
WN1684
WN1684
WN1684
The timetable & schedule information was updated at 2026-04-21
Via Denver with United Airlines
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Total flight time: 4h 49m - 7h 13m.
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129 flights per week
Flight
UA1481
UA1686
UA1254
UA1254
UA1254
UA1729
The timetable & schedule information was updated at 2026-04-21
Via Las Vegas with Southwest Airlines
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Total flight time: 5h 10m - 7h 20m.
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Low-cost airline
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Phoenix is a Southwest Airlines focus city (Operating base ).
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27 flights per week
Flight
WN4138
WN2104
The timetable & schedule information was updated at 2026-04-21
Via Dallas with American Airlines
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Total flight time: 5h 19m - 7h 38m.
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One World Alliance
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Phoenix is a American Airlines hub.
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118 flights per week
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Airbus A319Airbus A320
Flight
AA520
AA1685
AA1133
AA3239
AA2319
AA2319
The timetable & schedule information was updated at 2026-04-21

There are five airlines with scheduled flights between DSM and PHX. Both American Airlines and Southwest operates non-stop flights from Des Moines International to Phoenix Sky Harbor International and the flight time is 3 hours and 5 minutes.
Via Minneapolis with Delta
Via Denver with Frontier