Airlines with flights from Des Moines to Charlotte
There are four airlines with scheduled flights between DSM and CLT. American Airlines is the only airline with non-stop flights from Des Moines International to Charlotte Douglas and the flight time is 2 hours and 26 minutes.
There are four airlines with scheduled flights between DSM and CLT. American Airlines is the only airline with non-stop flights from Des Moines International to Charlotte Douglas and the flight time is 2 hours and 26 minutes. Choose airline
Direct
Non-stop
2h 26min
Via Chicago
3h 55min
Via Atlanta
4h 0min
Via Chicago
4h 10min
Via Detroit
4h 24min
Via Chicago
4h 26min
Via Minneapolis
4h 32min
Via Washington
4h 33min
Via Philadelphia
5h 15min
NEW
Via Washington
9h 45min
Schedules
Non-stop with American Airlines
-
Total flight time: 2 hours and 26 minutes
-
One World Alliance
-
Charlotte is a American Airlines hub.
-
14 flights per week
-
Airbus A320
-
First class available
DSM
Direct
CLT
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
AA2854
06:55
06:55
06:55
06:55
06:55
06:55
06:55
AA1763
13:37
13:37
13:37
13:37
13:37
13:37
13:37
The timetable & schedule information was updated at 2026-04-21
Via Chicago with Southwest Airlines
-
Total flight time: 3h 55m - 5h 50m.
-
Low-cost airline
-
25 flights per week
DSM
Via MDW
CLT
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
WN1772
WN2749
WN2749
05:10
05:20
05:20
05:10
05:10
05:10
----
WN1524
WN2752
WN2752
----
----
----
----
----
15:35
----
WN1524
WN4194
WN4194
----
15:45
15:45
----
----
----
16:15
WN1755
WN4194
WN4194
16:40
----
----
16:40
16:40
----
----
The timetable & schedule information was updated at 2026-04-21
Via Atlanta with Delta Air Lines
-
Total flight time: 4h 00m - 6h 23m.
-
Sky Team Alliance
-
83 flights per week
DSM
Via ATL
CLT
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
DL2727
DL3190
DL3190
05:25
05:25
05:25
05:25
05:25
05:51
05:25
DL1704
DL3158
DL3158
11:28
----
----
11:28
11:28
11:40
11:28
DL2094
DL720
DL720
14:48
----
----
14:48
14:48
----
14:48
DL2094
DL3139
DL3139
----
14:48
14:48
----
----
----
----
DL2086
DL3177
DL3177
18:39
18:39
18:39
18:39
18:39
16:47
18:39
The timetable & schedule information was updated at 2026-04-21
Via Chicago with American Airlines
-
Total flight time: 4h 10m - 6h 48m.
-
One World Alliance
-
Charlotte is a American Airlines hub.
-
114 flights per week
-
Airbus A320
DSM
Via ORD
CLT
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
AA4519
AA3222
AA3222
05:00
05:00
05:00
05:00
05:00
05:00
05:00
AA4969
AA2681
AA2681
08:43
08:43
08:43
08:43
08:43
08:43
08:43
AA4676
AA1683
AA1683
13:50
13:50
13:50
13:50
13:50
13:50
13:50
The timetable & schedule information was updated at 2026-04-21
Via Detroit with Delta Air Lines
-
Total flight time: 4h 24m - 5h 24m.
-
Sky Team Alliance
-
66 flights per week
DSM
Via DTW
CLT
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
DL5414
DL2684
DL2684
06:07
06:07
06:07
06:07
06:07
06:07
06:07
DL5048
DL1429
DL1429
10:23
10:23
10:23
10:23
10:23
----
10:23
The timetable & schedule information was updated at 2026-04-21
Via Chicago with United