Airlines with flights from Charlotte to Des Moines

There are four airlines with scheduled flights between CLT and DSM. American Airlines is the only airline with non-stop flights from Charlotte Douglas to Des Moines International and the flight time is 2 hours and 27 minutes.

Choose airline

Schedules

American Airlines

Non-stop with American Airlines

  • Total flight time: 2 hours and 27 minutes
  • One World Alliance
  • Charlotte is a American Airlines hub.
  • 17 flights per week
  • Airbus A320
  • First class available
CLT
Direct
DSM

The timetable & schedule information was updated at 2026-04-21

Southwest Airlines

Via Chicago with Southwest Airlines

  • Total flight time: 4h 00m - 5h 50m.
  • Low-cost airline
  • 40 flights per week
CLT
 
Via MDW
 
DSM
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
WN3048
WN1771
07:35
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07:35
07:35
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07:05
WN3048
WN1536
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07:50
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WN3711
WN1771
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08:20
08:20
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WN1513
WN4277
19:05
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----
19:05
19:05
18:00
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WN1513
WN41
----
19:05
19:05
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----
----
----
SHOW RETURN SCHEDULE
CHECK PRICES FOR CLT - DSM

The timetable & schedule information was updated at 2026-04-21

Delta Air Lines

Via Atlanta with Delta Air Lines

  • Total flight time: 4h 05m - 6h 35m.
  • Sky Team Alliance
  • 105 flights per week
CLT
 
Via ATL
 
DSM
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
DL3186
DL1704
05:30
05:30
05:30
05:30
05:30
06:00
05:30
DL2275
DL1704
06:59
06:59
06:59
06:59
06:59
07:00
06:59
DL3174
DL2094
09:42
09:42
09:42
09:42
09:42
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09:42
DL3190
DL2086
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12:19
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DL2157
DL2086
14:22
14:22
14:22
14:22
14:22
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14:22
DL3032
DL2306
16:56
17:39
17:39
16:56
16:56
17:39
16:56
SHOW RETURN SCHEDULE
CHECK PRICES FOR CLT - DSM

The timetable & schedule information was updated at 2026-04-21

American Airlines

Via Chicago with American Airlines

  • Total flight time: 4h 13m - 6h 47m.
  • One World Alliance
  • Charlotte is a American Airlines hub.
  • 163 flights per week
  • Airbus A320
CLT
 
Via ORD
 
DSM
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
AA2843
AA4676
07:44
07:44
07:44
07:44
07:44
07:44
07:44
AA1038
AA4676
09:30
09:30
09:30
09:30
09:30
09:30
09:30
AA2530
AA4973
13:05
13:05
13:05
13:05
13:05
13:05
13:05
AA2080
AA4973
14:41
14:41
14:41
14:41
14:41
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14:41
AA2080
AA4102
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14:46
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AA2907
AA4102
15:25
15:25
15:25
15:25
15:25
15:25
15:25
AA2488
AA4442
18:25
18:25
18:25
18:25
18:25
18:25
18:25
AA627
AA4442
20:10
20:10
20:10
20:10
20:10
20:10
20:10
SHOW RETURN SCHEDULE
CHECK PRICES FOR CLT - DSM

The timetable & schedule information was updated at 2026-04-21

Delta Air Lines

Via Detroit with Delta Air Lines

  • Total flight time: 4h 19m - 5h 22m.
  • Sky Team Alliance
  • 52 flights per week
CLT
 
Via DTW
 
DSM

The timetable & schedule information was updated at 2026-04-21

Staying up-to-date with the airlines

At Airlineinformation.com you can learn all about the airlines operating around the world together with their destinations and where they operate. You will get a transparent overview of airlines with scheduled flights between any two destinations with non-stop or 1-stop flights regardless of price or availability.
Flight data on this page was last updated on 2026-06-02