Airlines with flights from Saint Louis to Cleveland
There are four airlines with scheduled flights between STL and CLE. Southwest is the only airline with non-stop flights from Saint Louis Airport to Cleveland Hopkins International and the flight time is 1 hour and 30 minutes.
Choose airline
Schedules
Non-stop with Southwest Airlines
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Total flight time: 1 hour and 30 minutes
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Low-cost airline
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17 flights per week
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Boeing 737MAX 8 PassengerBoeing 737-700 Passenger (Scimitar Winglets)
STL
Direct
CLE
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
WN262
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----
----
----
----
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10:20
WN3899
12:50
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12:50
12:50
10:20
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WN908
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10:30
10:30
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----
----
----
WN349
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19:15
19:15
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----
----
----
WN263
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----
----
----
----
----
19:55
WN3900
20:55
----
----
20:55
20:55
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----
The timetable & schedule information was updated at 2026-04-21
Via Chicago with Southwest Airlines
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Total flight time: 2h 55m - 5h 15m.
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Low-cost airline
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83 flights per week
-
Boeing 737MAX 8 PassengerBoeing 737-700 Passenger (Scimitar Winglets)
STL
Via MDW
CLE
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
WN1008
WN937
WN937
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05:40
05:40
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----
----
----
WN1008
WN4088
WN4088
05:40
----
----
----
05:40
05:40
05:50
WN2570
WN1813
WN1813
08:55
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----
08:55
08:55
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09:05
WN2665
WN4088
WN4088
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09:40
09:40
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----
----
----
WN1373
WN4088
WN4088
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11:20
11:20
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----
----
----
WN556
WN4506
WN4506
15:35
----
----
15:35
15:35
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----
WN556
WN4153
WN4153
----
16:00
16:00
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----
----
16:40
WN2468
WN2587
WN2587
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----
----
----
----
16:00
----
The timetable & schedule information was updated at 2026-04-21
Via Detroit with Delta Air Lines
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Total flight time: 3h 05m - 5h 01m.
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Sky Team Alliance
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73 flights per week
STL
Via DTW
CLE
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
DL2868
DL3581
DL3581
10:20
10:20
10:20
10:20
10:20
10:20
10:20
DL1371
DL4954
DL4954
13:59
13:59
13:59
13:59
13:59
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13:59
DL2822
DL3646
DL3646
18:10
18:10
18:10
18:10
18:10
----
18:10
The timetable & schedule information was updated at 2026-04-21
Via Chicago with American Airlines
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Total flight time: 3h 17m - 6h 02m.
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One World Alliance
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226 flights per week
STL
Via ORD
CLE
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
AA4104
AA4949
AA4949
09:08
09:08
09:08
09:08
09:08
09:08
09:08
AA6352
AA3466
AA3466
13:45
13:45
13:45
13:45
13:45
13:45
13:45
AA3815
AA3466
AA3466
14:33
14:33
14:33
14:33
14:33
14:33
14:33
AA4537
AA1934
AA1934
17:00
17:00
17:00
17:00
17:00
17:14
17:00
The timetable & schedule information was updated at 2026-04-21
Via Nashville with Southwest Airlines
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Total flight time: 3h 20m - 5h 40m.
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Low-cost airline
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89 flights per week
-
Boeing 737MAX 8 PassengerBoeing 737-700 Passenger (Scimitar Winglets)
STL
Via BNA
CLE
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
WN3779
WN4571
WN4571
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08:05
WN1110
WN473
WN473
11:25
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11:25
11:25
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WN1860
WN224
WN224
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13:45
13:45
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----
----
----
WN996
WN474
WN474
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----
----
----
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16:40
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WN694
WN474
WN474
17:35
----
----
17:35
17:35
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18:15
The timetable & schedule information was updated at 2026-04-21

There are four airlines with scheduled flights between STL and CLE. Southwest is the only airline with non-stop flights from Saint Louis Airport to Cleveland Hopkins International and the flight time is 1 hour and 30 minutes.
Via Chicago with United