Airlines with flights from Louisville to San Francisco
There are five airlines with scheduled flights between SDF and SFO. Breeze is the only airline with non-stop flights from Louisville International Airport to SFO Airport and the flight time is 5 hours and 22 minutes.
Choose airline
Schedules
Non-stop with Breeze Airways
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Total flight time: 5 hours and 22 minutes
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2 flights per week
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Airbus A220-300
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First class available
SDF
Direct
SFO
W24, Jun 08 - Jun 14
Flight
Mon
Jun 8
Tue
Jun 9
Wed
Jun 10
Thu
Jun 11
Fri
Jun 12
Sat
Jun 13
Sun
Jun 14
MX228
09:31
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09:31
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The timetable & schedule information was updated at 2026-04-21
Via Denver with Southwest Airlines
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Total flight time: 6h 10m - 8h 25m.
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Low-cost airline
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18 flights per week
SDF
Via DEN
SFO
W24, Jun 08 - Jun 14
Flight
Mon
Jun 8
Tue
Jun 9
Wed
Jun 10
Thu
Jun 11
Fri
Jun 12
Sat
Jun 13
Sun
Jun 14
WN2117
WN3558
WN3558
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14:55
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The timetable & schedule information was updated at 2026-04-21
Via Denver with United Airlines
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Total flight time: 6h 30m - 8h 49m.
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San Francisco is a United Airlines hub.
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60 flights per week
SDF
Via DEN
SFO
W24, Jun 08 - Jun 14
Flight
Mon
Jun 8
Tue
Jun 9
Wed
Jun 10
Thu
Jun 11
Fri
Jun 12
Sat
Jun 13
Sun
Jun 14
UA1506
UA1561
UA1561
08:00
08:00
08:00
08:00
08:00
08:00
08:00
UA1510
UA1007
UA1007
15:25
15:25
15:25
15:25
15:25
15:25
15:25
The timetable & schedule information was updated at 2026-04-21
Via Phoenix with Southwest Airlines
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Total flight time: 6h 30m - 10h 15m.
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Low-cost airline
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27 flights per week
SDF
Via PHX
SFO
W24, Jun 08 - Jun 14
Flight
Mon
Jun 8
Tue
Jun 9
Wed
Jun 10
Thu
Jun 11
Fri
Jun 12
Sat
Jun 13
Sun
Jun 14
WN2236
WN2427
WN2427
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06:30
WN872
WN3334
WN3334
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10:55
10:55
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The timetable & schedule information was updated at 2026-04-21
Via Las Vegas with Southwest Airlines
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Total flight time: 6h 35m - 11h 20m.
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Low-cost airline
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21 flights per week
SDF
Via LAS
SFO
W24, Jun 08 - Jun 14
Flight
Mon
Jun 8
Tue
Jun 9
Wed
Jun 10
Thu
Jun 11
Fri
Jun 12
Sat
Jun 13
Sun
Jun 14
WN188
WN2345
WN2345
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19:55
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The timetable & schedule information was updated at 2026-04-21

There are five airlines with scheduled flights between SDF and SFO. Breeze is the only airline with non-stop flights from Louisville International Airport to SFO Airport and the flight time is 5 hours and 22 minutes.
Via Dallas with American Airlines
Via Minneapolis with Delta