Airlines with flights from Santiago to Guayaquil
LATAM is the only airline with non-stop flights from Santiago International Airport to Simon Bolivar International and the flight time is 5 hours and 18 minutes. You can also connect with LATAM via Lima with a flight time of 7 hours and 50 minutes.
Choose airline
Schedules
SCL
Direct
GYE
W27, Jun 29 - Jul 05
Flight
Mon
Jun 29
Tue
Jun 30
Wed
Jul 1
Thu
Jul 2
Fri
Jul 3
Sat
Jul 4
Sun
Jul 5
LA1446
00:37
00:29
00:45
00:45
00:45
00:45
00:45
The timetable & schedule information was updated at 2026-04-21
Via Lima with LATAM Airlines
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Total flight time: 7h 50m - 10h 05m.
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Santiago and Guayaquil are both LATAM Airlines hubs.
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94 flights per week
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Airbus A319
SCL
Via LIM
GYE
W27, Jun 29 - Jul 05
Flight
Mon
Jun 29
Tue
Jun 30
Wed
Jul 1
Thu
Jul 2
Fri
Jul 3
Sat
Jul 4
Sun
Jul 5
LA2378
LA1429
LA1429
----
----
05:40
05:40
05:40
05:40
05:40
LA528
LA1429
LA1429
05:40
05:40
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----
----
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LA642
LA1429
LA1429
----
----
----
07:25
07:25
----
07:25
LA650
LA1429
LA1429
07:45
07:45
07:50
07:50
07:50
07:50
07:50
LA2696
LA1449
LA1449
16:50
16:50
16:50
16:50
16:50
16:50
16:50
LA2412
LA1449
LA1449
----
----
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18:00
18:10
18:00
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LA2430
LA1449
LA1449
----
----
18:45
18:45
18:45
18:45
18:45
LA524
LA1449
LA1449
18:45
18:45
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The timetable & schedule information was updated at 2026-04-21

LATAM is the only airline with non-stop flights from Santiago International Airport to Simon Bolivar International and the flight time is 5 hours and 18 minutes. You can also connect with LATAM via Lima with a flight time of 7 hours and 50 minutes.