Airlines with flights from Fort Myers to Saint Louis
There are four airlines with scheduled flights between RSW and STL. Southwest is the only airline with non-stop flights from Southwest Florida International Airport to Saint Louis Airport and the flight time is 2 hours and 35 minutes.
Choose airline
Schedules
Non-stop with Southwest Airlines
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Total flight time: 2 hours and 35 minutes
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Low-cost airline
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19 flights per week
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Boeing 737MAX 8 PassengerBoeing 737-800 (winglets) Passenger/BBJ2Boeing 737-700 Passenger (Scimitar Winglets)
RSW
Direct
STL
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
WN3471
05:55
06:00
06:00
05:55
05:55
08:05
06:00
WN3699
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----
----
----
----
14:00
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WN3472
19:20
18:55
18:55
19:20
19:20
20:45
19:30
The timetable & schedule information was updated at 2026-04-22
Via Nashville with Southwest Airlines
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Total flight time: 4h 00m - 6h 10m.
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Low-cost airline
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66 flights per week
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Boeing 737MAX 8 PassengerBoeing 737-800 (winglets) Passenger/BBJ2Boeing 737-700 Passenger (Scimitar Winglets)
RSW
Via BNA
STL
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
WN3461
WN1371
WN1371
09:30
----
----
09:30
09:30
----
----
WN381
WN1371
WN1371
----
11:25
11:25
----
----
----
----
WN3462
WN682
WN682
21:05
----
----
21:05
21:05
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20:45
The timetable & schedule information was updated at 2026-04-22
Via Orlando with Southwest Airlines
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Total flight time: 4h 05m - 8h 10m.
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Low-cost airline
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75 flights per week
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Boeing 737MAX 8 PassengerBoeing 737-800 (winglets) Passenger/BBJ2Boeing 737-700 Passenger (Scimitar Winglets)
RSW
Via MCO
STL
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
WN4872
WN4501
WN4501
06:15
06:10
06:10
06:15
06:15
----
06:10
WN4872
WN2570
WN2570
----
----
----
----
----
06:20
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The timetable & schedule information was updated at 2026-04-22
Via Atlanta with Delta Air Lines
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Total flight time: 4h 06m - 6h 31m.
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Sky Team Alliance
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188 flights per week
RSW
Via ATL
STL
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
DL1385
DL1400
DL1400
05:37
05:37
05:37
05:37
05:37
----
05:37
DL1395
DL566
DL566
08:03
08:03
08:03
08:03
08:03
08:30
08:03
DL1089
DL2700
DL2700
10:53
10:53
10:53
10:53
10:53
10:38
10:38
DL1153
DL1393
DL1393
13:19
13:19
13:19
13:19
13:19
13:19
13:19
DL1349
DL2833
DL2833
18:34
----
18:34
18:34
18:34
----
18:34
DL1349
DL1403
DL1403
----
18:34
----
----
----
18:34
----
DL1124
DL1403
DL1403
19:58
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----
19:58
19:58
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19:58
The timetable & schedule information was updated at 2026-04-22
Via Charlotte with American Airlines
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Total flight time: 4h 27m - 6h 59m.
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One World Alliance
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241 flights per week
RSW
Via CLT
STL
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
AA1097
AA2717
AA2717
06:15
06:15
06:15
06:15
06:15
06:00
06:15
AA2444
AA2686
AA2686
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----
----
----
----
15:57
15:57
AA2442
AA459
AA459
19:35
----
----
19:35
19:35
19:35
19:35
The timetable & schedule information was updated at 2026-04-22

There are four airlines with scheduled flights between RSW and STL. Southwest is the only airline with non-stop flights from Southwest Florida International Airport to Saint Louis Airport and the flight time is 2 hours and 35 minutes.
Via Chicago with United