Airlines with flights from Fort Myers to Saint Louis

There are four airlines with scheduled flights between RSW and STL. Southwest is the only airline with non-stop flights from Southwest Florida International Airport to Saint Louis Airport and the flight time is 2 hours and 35 minutes.

Choose airline

Schedules

Southwest Airlines

Non-stop with Southwest Airlines

  • Total flight time: 2 hours and 35 minutes
  • Low-cost airline
  • 19 flights per week
  • Boeing 737MAX 8 Passenger
    Boeing 737-800 (winglets) Passenger/BBJ2
    Boeing 737-700 Passenger (Scimitar Winglets)
RSW
Direct
STL

The timetable & schedule information was updated at 2026-04-22

Southwest Airlines

Via Nashville with Southwest Airlines

  • Total flight time: 4h 00m - 6h 10m.
  • Low-cost airline
  • 66 flights per week
  • Boeing 737MAX 8 Passenger
    Boeing 737-800 (winglets) Passenger/BBJ2
    Boeing 737-700 Passenger (Scimitar Winglets)
RSW
 
Via BNA
 
STL

The timetable & schedule information was updated at 2026-04-22

Southwest Airlines

Via Orlando with Southwest Airlines

  • Total flight time: 4h 05m - 8h 10m.
  • Low-cost airline
  • 75 flights per week
  • Boeing 737MAX 8 Passenger
    Boeing 737-800 (winglets) Passenger/BBJ2
    Boeing 737-700 Passenger (Scimitar Winglets)
RSW
 
Via MCO
 
STL

The timetable & schedule information was updated at 2026-04-22

Delta Air Lines

Via Atlanta with Delta Air Lines

  • Total flight time: 4h 06m - 6h 31m.
  • Sky Team Alliance
  • 188 flights per week
RSW
 
Via ATL
 
STL
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
DL1385
DL1400
05:37
05:37
05:37
05:37
05:37
----
05:37
DL1395
DL566
08:03
08:03
08:03
08:03
08:03
08:30
08:03
DL1089
DL2700
10:53
10:53
10:53
10:53
10:53
10:38
10:38
DL1153
DL1393
13:19
13:19
13:19
13:19
13:19
13:19
13:19
DL1349
DL2833
18:34
----
18:34
18:34
18:34
----
18:34
DL1349
DL1403
----
18:34
----
----
----
18:34
----
DL1124
DL1403
19:58
----
----
19:58
19:58
----
19:58
SHOW RETURN SCHEDULE
CHECK PRICES FOR RSW - STL

The timetable & schedule information was updated at 2026-04-22

American Airlines

Via Charlotte with American Airlines

  • Total flight time: 4h 27m - 6h 59m.
  • One World Alliance
  • 241 flights per week
RSW
 
Via CLT
 
STL

The timetable & schedule information was updated at 2026-04-22

Staying up-to-date with the airlines

At Airlineinformation.com you can learn all about the airlines operating around the world together with their destinations and where they operate. You will get a transparent overview of airlines with scheduled flights between any two destinations with non-stop or 1-stop flights regardless of price or availability.
Flight data on this page was last updated on 2026-06-02