Airlines with flights from Fort Myers to Louisville
There are five airlines with scheduled flights between RSW and SDF. Breeze is the only airline with non-stop flights from Southwest Florida International Airport to Louisville International Airport and the flight time is 2 hours and 32 minutes.
Choose airline
Schedules
Non-stop with Breeze Airways
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Total flight time: 2 hours and 32 minutes
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2 flights per week
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Airbus A220-300
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First class available
RSW
Direct
SDF
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
MX752
18:19
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18:19
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The timetable & schedule information was updated at 2026-04-22
Via Orlando with Southwest Airlines
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Total flight time: 3h 45m - 6h 55m.
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Low-cost airline
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75 flights per week
RSW
Via MCO
SDF
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
WN4872
WN872
WN872
06:15
06:10
06:10
06:15
06:15
06:20
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WN4872
WN2085
WN2085
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06:10
The timetable & schedule information was updated at 2026-04-22
Via Atlanta with Delta Air Lines
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Total flight time: 3h 48m - 6h 20m.
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Sky Team Alliance
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193 flights per week
RSW
Via ATL
SDF
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
DL1385
DL1374
DL1374
05:37
05:37
05:37
05:37
05:37
06:00
05:37
DL1361
DL1481
DL1481
06:50
06:50
06:50
06:50
06:50
07:04
06:50
DL1089
DL3195
DL3195
10:53
10:53
10:53
10:53
10:53
10:38
10:38
DL1153
DL1126
DL1126
13:19
13:19
13:19
13:19
13:19
13:19
13:19
DL1196
DL3093
DL3093
15:50
15:50
15:50
15:50
15:50
15:45
15:45
DL1349
DL2624
DL2624
18:34
18:34
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18:34
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DL1349
DL2842
DL2842
18:34
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----
18:34
18:34
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18:34
DL1124
DL2624
DL2624
19:58
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19:58
19:58
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19:58
The timetable & schedule information was updated at 2026-04-22
Via Charlotte with American Airlines
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Total flight time: 3h 53m - 6h 37m.
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One World Alliance
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252 flights per week
RSW
Via CLT
SDF
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
AA1097
AA5922
AA5922
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----
----
----
----
06:00
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AA1097
AA5395
AA5395
06:15
06:15
06:15
06:15
06:15
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06:15
AA2427
AA5397
AA5397
09:58
09:58
09:58
09:58
09:58
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10:00
AA2427
AA5923
AA5923
----
----
----
----
----
09:58
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AA2444
AA5161
AA5161
15:57
15:57
15:57
15:57
15:57
15:57
15:57
AA2442
AA671
AA671
19:35
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19:35
19:35
19:35
19:35
The timetable & schedule information was updated at 2026-04-22
Via Nashville with Southwest Airlines
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Total flight time: 3h 55m - 6h 00m.
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Low-cost airline
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13 flights per week
RSW
Via BNA
SDF
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
WN2216
WN671
WN671
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16:40
16:40
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The timetable & schedule information was updated at 2026-04-22

There are five airlines with scheduled flights between RSW and SDF. Breeze is the only airline with non-stop flights from Southwest Florida International Airport to Louisville International Airport and the flight time is 2 hours and 32 minutes.
Via Chicago with United