Airlines with flights from Fort Myers to Louisville

There are five airlines with scheduled flights between RSW and SDF. Breeze is the only airline with non-stop flights from Southwest Florida International Airport to Louisville International Airport and the flight time is 2 hours and 32 minutes.

Choose airline

Schedules

Breeze Airways

Non-stop with Breeze Airways

  • Total flight time: 2 hours and 32 minutes
  • 2 flights per week
  • Airbus A220-300
  • First class available
RSW
Direct
SDF

The timetable & schedule information was updated at 2026-04-22

Southwest Airlines

Via Orlando with Southwest Airlines

  • Total flight time: 3h 45m - 6h 55m.
  • Low-cost airline
  • 75 flights per week
RSW
 
Via MCO
 
SDF

The timetable & schedule information was updated at 2026-04-22

Delta Air Lines

Via Atlanta with Delta Air Lines

  • Total flight time: 3h 48m - 6h 20m.
  • Sky Team Alliance
  • 193 flights per week
RSW
 
Via ATL
 
SDF
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
DL1385
DL1374
05:37
05:37
05:37
05:37
05:37
06:00
05:37
DL1361
DL1481
06:50
06:50
06:50
06:50
06:50
07:04
06:50
DL1089
DL3195
10:53
10:53
10:53
10:53
10:53
10:38
10:38
DL1153
DL1126
13:19
13:19
13:19
13:19
13:19
13:19
13:19
DL1196
DL3093
15:50
15:50
15:50
15:50
15:50
15:45
15:45
DL1349
DL2624
18:34
18:34
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----
18:34
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DL1349
DL2842
18:34
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----
18:34
18:34
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18:34
DL1124
DL2624
19:58
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----
19:58
19:58
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19:58
SHOW RETURN SCHEDULE
CHECK PRICES FOR RSW - SDF

The timetable & schedule information was updated at 2026-04-22

American Airlines

Via Charlotte with American Airlines

  • Total flight time: 3h 53m - 6h 37m.
  • One World Alliance
  • 252 flights per week
RSW
 
Via CLT
 
SDF
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
AA1097
AA5922
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----
----
----
----
06:00
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AA1097
AA5395
06:15
06:15
06:15
06:15
06:15
----
06:15
AA2427
AA5397
09:58
09:58
09:58
09:58
09:58
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10:00
AA2427
AA5923
----
----
----
----
----
09:58
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AA2444
AA5161
15:57
15:57
15:57
15:57
15:57
15:57
15:57
AA2442
AA671
19:35
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----
19:35
19:35
19:35
19:35
SHOW RETURN SCHEDULE
CHECK PRICES FOR RSW - SDF

The timetable & schedule information was updated at 2026-04-22

Southwest Airlines

Via Nashville with Southwest Airlines

  • Total flight time: 3h 55m - 6h 00m.
  • Low-cost airline
  • 13 flights per week
RSW
 
Via BNA
 
SDF

The timetable & schedule information was updated at 2026-04-22

Staying up-to-date with the airlines

At Airlineinformation.com you can learn all about the airlines operating around the world together with their destinations and where they operate. You will get a transparent overview of airlines with scheduled flights between any two destinations with non-stop or 1-stop flights regardless of price or availability.
Flight data on this page was last updated on 2026-06-02