Airlines with flights from Raleigh/Durham to San Diego
There are 8 airlines with scheduled flights between RDU and SAN. Both Alaska Airlines and Breeze operates non-stop flights from Raleigh–Durham Airport to San Diego International Airport and the flight time is 5 hours and 18 minutes.
Choose airline
Schedules
Non-stop with Alaska Airlines
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Total flight time: 5 hours and 18 minutes
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One World Alliance
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San Diego is a Alaska Airlines focus city.
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7 flights per week
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Boeing 737MAX 9 Passenger
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Business and first class available
Flight
The timetable & schedule information was updated at 2026-04-21
Non-stop with Breeze Airways
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Total flight time: 5 hours and 49 minutes
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3 flights per week
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Airbus A220-300
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First class available
Flight
The timetable & schedule information was updated at 2026-04-21
Via Nashville with Southwest Airlines
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Total flight time: 6h 25m - 11h 35m.
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Low-cost airline
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77 flights per week
Flight
WN659
WN4111
WN4253
WN3888
WN1978
The timetable & schedule information was updated at 2026-04-21
Via Phoenix with Southwest Airlines
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Total flight time: 6h 25m - 9h 00m.
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Low-cost airline
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50 flights per week
Flight
WN3017
WN1202
WN3332
WN4052
The timetable & schedule information was updated at 2026-04-21
Via Saint Louis with Southwest Airlines
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Total flight time: 6h 25m - 10h 10m.
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Low-cost airline
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35 flights per week
Flight
WN4283
WN2528
WN1959
The timetable & schedule information was updated at 2026-04-21
Via Austin with Southwest Airlines
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Total flight time: 6h 30m - 10h 00m.
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Low-cost airline
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58 flights per week
Flight
WN392
WN167
The timetable & schedule information was updated at 2026-04-21

There are 8 airlines with scheduled flights between RDU and SAN. Both Alaska Airlines and Breeze operates non-stop flights from Raleigh–Durham Airport to San Diego International Airport and the flight time is 5 hours and 18 minutes.
Via Charlotte with American Airlines
Via Atlanta with Delta
Via Denver with United
Via Denver with Frontier
Via Minneapolis with Sun Country Airlines