Airlines with flights from Mexico City to Panama City

There are three airlines with scheduled flights between MEX and PTY. Both Copa Airlines and Aeromexico operates non-stop flights from Mexico City International Airport to Tocumen International and the flight time is 3 hours and 44 minutes. You can also connect with AVIANCA via San Salvador with a flight time of 5 hours and 30 minutes.

Choose airline

Schedules

Copa Airlines

Non-stop with Copa Airlines

  • Total flight time: 3 hours and 44 minutes
  • Panama City is a Copa Airlines hub.
  • 41 flights per week
  • Boeing 737MAX 8 Passenger
    Boeing 737-800 Passenger
  • Business class available
MEX
Direct
PTY
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
CM863
----
00:25
00:25
00:25
----
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00:25
CM149
01:20
01:20
01:20
01:20
01:20
01:20
01:20
CM857
02:10
02:10
02:10
02:10
02:10
----
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CM195
05:50
05:50
05:50
05:50
05:50
05:50
05:50
CM137
09:50
09:50
09:50
09:50
09:50
09:50
09:50
CM121
13:10
13:10
13:10
13:10
13:10
13:10
13:10
CM135
15:30
15:30
15:30
15:30
15:30
15:30
15:30
SHOW RETURN SCHEDULE
CHECK PRICES FOR MEX - PTY

The timetable & schedule information was updated at 2026-04-21

Aeromexico

Non-stop with Aeromexico

  • Total flight time: 4 hours
  • Sky Team Alliance
  • Mexico City is a Aeromexico hub.
  • 7 flights per week
  • Boeing 737-800 (Scimitar Winglets) Passenger
    Embraer 190
  • Business class available
MEX
Direct
PTY

The timetable & schedule information was updated at 2026-04-21

AVIANCA

Via San Salvador with AVIANCA

  • Total flight time: 5h 30m - 8h 00m.
  • 11 flights per week
MEX
 
Via SAL
 
PTY

The timetable & schedule information was updated at 2026-04-21

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Flight data on this page was last updated on 2026-06-02