Airlines with flights from Mexico City to Panama City
There are three airlines with scheduled flights between MEX and PTY. Both Copa Airlines and Aeromexico operates non-stop flights from Mexico City International Airport to Tocumen International and the flight time is 3 hours and 44 minutes. You can also connect with AVIANCA via San Salvador with a flight time of 5 hours and 30 minutes.
Choose airline
Schedules
Non-stop with Copa Airlines
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Total flight time: 3 hours and 44 minutes
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Panama City is a Copa Airlines hub.
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41 flights per week
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Boeing 737MAX 8 PassengerBoeing 737-800 Passenger
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Business class available
MEX
Direct
PTY
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
CM863
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00:25
00:25
00:25
----
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00:25
CM149
01:20
01:20
01:20
01:20
01:20
01:20
01:20
CM857
02:10
02:10
02:10
02:10
02:10
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CM195
05:50
05:50
05:50
05:50
05:50
05:50
05:50
CM137
09:50
09:50
09:50
09:50
09:50
09:50
09:50
CM121
13:10
13:10
13:10
13:10
13:10
13:10
13:10
CM135
15:30
15:30
15:30
15:30
15:30
15:30
15:30
The timetable & schedule information was updated at 2026-04-21
Non-stop with Aeromexico
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Total flight time: 4 hours
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Sky Team Alliance
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Mexico City is a Aeromexico hub.
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7 flights per week
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Boeing 737-800 (Scimitar Winglets) PassengerEmbraer 190
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Business class available
MEX
Direct
PTY
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
AM464
09:00
09:00
09:00
09:00
09:00
09:00
09:00
The timetable & schedule information was updated at 2026-04-21
Via San Salvador with AVIANCA
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Total flight time: 5h 30m - 8h 00m.
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11 flights per week
MEX
Via SAL
PTY
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
AV433
AV323
AV323
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04:00
----
04:00
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04:00
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AV431
AV317
AV317
16:55
16:55
16:55
16:55
16:55
16:55
16:55
The timetable & schedule information was updated at 2026-04-21

There are three airlines with scheduled flights between MEX and PTY. Both Copa Airlines and Aeromexico operates non-stop flights from Mexico City International Airport to Tocumen International and the flight time is 3 hours and 44 minutes. You can also connect with AVIANCA via San Salvador with a flight time of 5 hours and 30 minutes.