Airlines with flights from Chicago to Des Moines
There are two airlines with scheduled flights between MDW and DSM. Southwest is the only airline with non-stop flights from Midway International Airport to Des Moines International and the flight time is 1 hour and 25 minutes. You can also connect with Delta via Minneapolis with a flight time of 3 hours and 49 minutes.
Choose airline
Schedules
Non-stop with Southwest Airlines
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Total flight time: 1 hour and 25 minutes
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Low-cost airline
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Chicago is a Southwest Airlines focus city (Operating base).
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18 flights per week
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Boeing 737MAX 8 PassengerBoeing 737-700 Passenger (Scimitar Winglets)Boeing 737-800 (winglets) Passenger/BBJ2
MDW
Direct
DSM
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
WN1771
10:10
10:10
10:10
10:10
10:10
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10:05
WN1536
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10:15
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WN41
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21:20
21:20
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WN4277
22:05
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22:05
22:05
21:25
22:25
The timetable & schedule information was updated at 2026-04-21
Via Minneapolis with Delta Air Lines
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Total flight time: 3h 49m - 4h 47m.
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Sky Team Alliance
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20 flights per week
MDW
Via MSP
DSM
W25, Jun 15 - Jun 21
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
DL5469
DL5490
DL5490
09:54
09:54
09:54
09:54
09:54
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09:54
The timetable & schedule information was updated at 2026-04-21

There are two airlines with scheduled flights between MDW and DSM. Southwest is the only airline with non-stop flights from Midway International Airport to Des Moines International and the flight time is 1 hour and 25 minutes. You can also connect with Delta via Minneapolis with a flight time of 3 hours and 49 minutes.