Airlines with flights from Chicago to Buffalo

There are two airlines with scheduled flights between MDW and BUF. Southwest is the only airline with non-stop flights from Midway International Airport to Buffalo Niagara International and the flight time is 1 hour and 30 minutes.

Change direction

Choose airline

Schedules

Southwest Airlines

Non-stop with Southwest Airlines

  • Total flight time: 1 hour and 30 minutes
  • Low-cost airline
  • Chicago is a Southwest Airlines focus city (Operating base).
  • 25 flights per week
  • Boeing 737-700 Passenger (Scimitar Winglets)
    Boeing 737MAX 8 Passenger
    Boeing 737-800 (winglets) Passenger/BBJ2
MDW
Direct
BUF
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
WN748
----
----
----
----
----
----
07:45
WN758
07:55
07:50
07:50
07:55
07:55
07:45
----
WN1655
13:00
----
----
13:00
13:00
----
12:10
WN807
----
----
----
----
----
12:55
----
WN958
----
13:15
13:15
----
----
----
----
WN2730
----
----
----
----
----
17:50
----
WN4110
19:05
----
----
19:05
19:05
----
18:50
WN2659
----
18:55
18:55
----
----
----
----
SHOW RETURN SCHEDULE
CHECK PRICES FOR MDW - BUF

The timetable & schedule information was updated at 2026-04-21

Delta Air Lines

Via Detroit with Delta Air Lines

  • Total flight time: 3h 01m - 5h 04m.
  • Sky Team Alliance
  • 58 flights per week
MDW
 
Via DTW
 
BUF
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
DL4674
DL3642
09:17
09:17
09:17
09:17
09:17
09:17
09:17
DL4688
DL3637
13:16
13:16
13:16
13:16
13:16
----
13:16
DL4690
DL978
18:58
18:58
18:58
18:58
18:58
18:35
18:58
SHOW RETURN SCHEDULE
CHECK PRICES FOR MDW - BUF

The timetable & schedule information was updated at 2026-04-21

Southwest Airlines

Via Baltimore with Southwest Airlines

  • Total flight time: 3h 45m - 8h 40m.
  • Low-cost airline
  • Chicago is a Southwest Airlines focus city (Operating base).
  • 158 flights per week
  • Boeing 737-700 Passenger (Scimitar Winglets)
    Boeing 737MAX 8 Passenger
    Boeing 737-800 (winglets) Passenger/BBJ2
MDW
 
Via BWI
 
BUF
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
WN2706
WN762
----
----
----
----
----
----
05:05
WN2742
WN762
07:00
----
----
07:00
07:00
05:15
----
WN1120
WN279
----
06:00
06:00
----
----
----
----
WN1267
WN894
07:45
----
----
07:45
07:45
----
----
WN174
WN768
----
----
----
----
----
07:45
----
WN937
WN766
----
07:50
07:50
----
----
----
----
WN1355
WN766
----
08:10
08:10
----
----
----
----
WN925
WN186
----
----
----
----
----
08:25
----
WN4070
WN894
----
----
----
----
----
----
08:50
WN1355
WN894
08:55
----
----
08:55
08:55
----
----
WN2779
WN768
----
----
----
----
----
10:20
----
WN2744
WN768
----
----
----
----
----
----
12:10
WN1159
WN1742
----
12:45
12:45
----
----
----
----
WN1526
WN1742
----
12:55
12:55
----
----
----
----
WN1247
WN768
13:00
----
----
13:00
13:00
----
----
WN2877
WN1742
----
13:10
13:10
----
----
----
----
WN554
WN3946
----
16:10
16:10
----
----
----
----
WN235
WN4577
----
----
----
----
----
16:50
----
WN4616
WN4577
17:20
----
----
17:20
17:20
----
----
WN2745
WN3946
----
17:30
17:30
----
----
----
----
WN1107
WN1593
----
----
----
----
----
----
18:30
WN2745
WN4577
19:00
----
----
19:00
19:00
----
----
SHOW RETURN SCHEDULE
CHECK PRICES FOR MDW - BUF

The timetable & schedule information was updated at 2026-04-21

Southwest Airlines

Via Saint Louis with Southwest Airlines

  • Total flight time: 6h 40m - 7h 00m.
  • Low-cost airline
  • Chicago is a Southwest Airlines focus city (Operating base).
  • 2 flights per week
  • Boeing 737-700 Passenger (Scimitar Winglets)
    Boeing 737MAX 8 Passenger
    Boeing 737-800 (winglets) Passenger/BBJ2
MDW
 
Via STL
 
BUF
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
SHOW RETURN SCHEDULE
CHECK PRICES FOR MDW - BUF

The timetable & schedule information was updated at 2026-04-21

Change direction

Staying up-to-date with the airlines

At Airlineinformation.com you can learn all about the airlines operating around the world together with their destinations and where they operate. You will get a transparent overview of airlines with scheduled flights between any two destinations with non-stop or 1-stop flights regardless of price or availability.
Flight data on this page was last updated on 2026-06-02
© 2026 Westcoast Digital