Airlines with flights from Orlando to Saint Louis
There are five airlines with scheduled flights between MCO and STL. Both Southwest and Frontier operates non-stop flights from Orlando International to Saint Louis Airport and the flight time is 2 hours and 35 minutes.
Choose airline
Schedules
Non-stop with Southwest Airlines
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Total flight time: 2 hours and 35 minutes
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Low-cost airline
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Orlando is a Southwest Airlines focus city (Operating base ).
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50 flights per week
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Boeing 737MAX 8 PassengerBoeing 737-700 Passenger (Scimitar Winglets)Boeing 737-800 (winglets) Passenger/BBJ2
Flight
The timetable & schedule information was updated at 2026-04-21
Non-stop with Frontier Airlines
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Total flight time: 2 hours and 41 minutes
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Low-cost airline
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Orlando is a Frontier Airlines focus city (Operating base).
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17 flights per week
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Airbus A321neo
Flight
The timetable & schedule information was updated at 2026-04-21
Via Atlanta with Southwest Airlines
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Total flight time: 3h 40m - 6h 15m.
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Low-cost airline
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Orlando is a Southwest Airlines focus city (Operating base ).
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25 flights per week
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Boeing 737MAX 8 PassengerBoeing 737-700 Passenger (Scimitar Winglets)Boeing 737-800 (winglets) Passenger/BBJ2
Flight
WN266
The timetable & schedule information was updated at 2026-04-21
Via Nashville with Southwest Airlines
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Total flight time: 3h 50m - 8h 15m.
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Low-cost airline
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Orlando is a Southwest Airlines focus city (Operating base ).
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150 flights per week
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Boeing 737MAX 8 PassengerBoeing 737-700 Passenger (Scimitar Winglets)Boeing 737-800 (winglets) Passenger/BBJ2
Flight
WN1371
WN1371
WN1371
WN770
WN770
WN682
WN682
WN682
WN682
WN682
The timetable & schedule information was updated at 2026-04-21
Via Charlotte with American Airlines
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Total flight time: 4h 03m - 7h 05m.
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One World Alliance
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140 flights per week
Flight
AA5345
AA2733
AA2717
AA2717
AA2731
AA2731
AA2731
AA2686
AA459
AA459
The timetable & schedule information was updated at 2026-04-21
Via Atlanta with Delta Air Lines
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Total flight time: 4h 10m - 6h 34m.
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Sky Team Alliance
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197 flights per week
Flight
DL1400
DL1400
DL566
DL566
DL2700
DL2700
DL543
DL1393
DL1393
DL2833
DL2833
DL1403
DL1403
The timetable & schedule information was updated at 2026-04-21

There are five airlines with scheduled flights between MCO and STL. Both Southwest and Frontier operates non-stop flights from Orlando International to Saint Louis Airport and the flight time is 2 hours and 35 minutes.
Via Chicago with United