Airlines with flights from Orlando to Saint Louis

There are five airlines with scheduled flights between MCO and STL. Both Southwest and Frontier operates non-stop flights from Orlando International to Saint Louis Airport and the flight time is 2 hours and 35 minutes.

Choose airline

Schedules

Southwest Airlines

Non-stop with Southwest Airlines

  • Total flight time: 2 hours and 35 minutes
  • Low-cost airline
  • Orlando is a Southwest Airlines focus city (Operating base ).
  • 50 flights per week
  • Boeing 737MAX 8 Passenger
    Boeing 737-700 Passenger (Scimitar Winglets)
    Boeing 737-800 (winglets) Passenger/BBJ2
MCO
Direct
STL
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
WN2615
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06:10
06:10
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WN2570
06:50
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06:50
06:50
07:55
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WN2828
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06:55
WN4501
08:50
08:50
08:50
08:50
08:50
09:20
08:55
WN3316
11:10
13:45
13:45
11:10
11:10
12:00
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WN1530
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13:55
WN5048
14:05
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14:05
14:05
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WN1726
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15:00
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WN4287
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15:35
WN3236
19:00
18:40
18:40
19:00
19:00
18:15
18:10
WN142
22:35
21:40
21:40
22:35
22:35
21:55
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WN198
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----
----
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22:15
SHOW RETURN SCHEDULE
CHECK PRICES FOR MCO - STL

The timetable & schedule information was updated at 2026-04-21

Frontier Airlines

Non-stop with Frontier Airlines

  • Total flight time: 2 hours and 41 minutes
  • Low-cost airline
  • Orlando is a Frontier Airlines focus city (Operating base).
  • 17 flights per week
  • Airbus A321neo
MCO
Direct
STL

The timetable & schedule information was updated at 2026-04-21

Southwest Airlines

Via Atlanta with Southwest Airlines

  • Total flight time: 3h 40m - 6h 15m.
  • Low-cost airline
  • Orlando is a Southwest Airlines focus city (Operating base ).
  • 25 flights per week
  • Boeing 737MAX 8 Passenger
    Boeing 737-700 Passenger (Scimitar Winglets)
    Boeing 737-800 (winglets) Passenger/BBJ2
MCO
 
Via ATL
 
STL

The timetable & schedule information was updated at 2026-04-21

Southwest Airlines

Via Nashville with Southwest Airlines

  • Total flight time: 3h 50m - 8h 15m.
  • Low-cost airline
  • Orlando is a Southwest Airlines focus city (Operating base ).
  • 150 flights per week
  • Boeing 737MAX 8 Passenger
    Boeing 737-700 Passenger (Scimitar Winglets)
    Boeing 737-800 (winglets) Passenger/BBJ2
MCO
 
Via BNA
 
STL
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
WN684
WN1371
08:20
08:00
08:00
08:20
08:20
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WN2604
WN1371
09:35
09:35
09:35
09:35
09:35
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12:35
WN4713
WN1371
11:00
10:55
10:55
11:00
11:00
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WN410
WN770
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14:10
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WN673
WN770
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----
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----
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16:40
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WN2839
WN682
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17:10
17:10
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WN2607
WN682
19:40
18:15
18:15
19:40
19:40
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WN2071
WN682
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18:50
WN4711
WN682
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----
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19:00
WN2608
WN682
20:45
19:45
19:45
20:45
20:45
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20:35
SHOW RETURN SCHEDULE
CHECK PRICES FOR MCO - STL

The timetable & schedule information was updated at 2026-04-21

American Airlines

Via Charlotte with American Airlines

  • Total flight time: 4h 03m - 7h 05m.
  • One World Alliance
  • 140 flights per week
MCO
 
Via CLT
 
STL
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
AA1896
AA5345
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05:00
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AA1896
AA2733
05:00
05:00
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----
05:00
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05:00
AA461
AA2717
06:15
06:15
06:15
06:15
06:15
06:15
06:15
AA1525
AA2717
08:00
08:00
08:00
08:00
08:00
08:00
08:00
AA2073
AA2731
11:40
11:40
11:40
11:40
11:40
11:40
11:40
AA2074
AA2731
12:48
12:48
12:48
12:48
12:48
12:48
12:48
AA2127
AA2731
13:55
13:55
13:55
13:55
13:55
13:55
13:55
AA2098
AA2686
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----
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----
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15:32
15:32
AA2082
AA459
17:39
17:39
17:39
17:39
17:39
17:39
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AA2100
AA459
19:32
19:32
19:32
19:32
19:32
19:55
19:32
SHOW RETURN SCHEDULE
CHECK PRICES FOR MCO - STL

The timetable & schedule information was updated at 2026-04-21

Delta Air Lines

Via Atlanta with Delta Air Lines

  • Total flight time: 4h 10m - 6h 34m.
  • Sky Team Alliance
  • 197 flights per week
MCO
 
Via ATL
 
STL
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
DL1548
DL1400
05:30
05:30
05:30
05:30
05:30
05:30
05:30
DL1494
DL1400
06:15
06:15
06:15
06:15
06:15
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06:15
DL1463
DL566
08:05
08:05
08:05
08:05
08:05
08:05
08:05
DL1505
DL566
09:05
09:05
09:05
09:05
09:05
09:05
09:05
DL2204
DL2700
10:05
10:05
10:05
10:05
10:05
10:05
10:05
DL1213
DL2700
11:05
11:05
11:05
11:05
11:05
11:05
11:05
DL1658
DL543
12:05
12:05
12:05
12:05
12:05
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12:05
DL664
DL1393
13:05
13:05
13:05
13:05
13:05
13:05
13:05
DL1030
DL1393
14:05
14:05
14:05
14:05
14:05
14:05
14:05
DL1642
DL2833
16:45
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16:45
16:45
16:45
16:45
16:45
DL1150
DL2833
17:45
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17:45
17:45
17:45
17:45
17:45
DL1742
DL1403
18:45
18:45
18:45
18:45
18:45
18:45
18:45
DL1497
DL1403
19:55
19:55
19:55
19:55
19:55
19:55
19:55
SHOW RETURN SCHEDULE
CHECK PRICES FOR MCO - STL

The timetable & schedule information was updated at 2026-04-21

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At Airlineinformation.com you can learn all about the airlines operating around the world together with their destinations and where they operate. You will get a transparent overview of airlines with scheduled flights between any two destinations with non-stop or 1-stop flights regardless of price or availability.
Flight data on this page was last updated on 2026-06-02