Airlines with flights from Madrid to Santiago

There are four airlines with scheduled flights between MAD and STI. Air Europa is the only airline with non-stop flights from Barajas to Cibao International and the flight time is 8 hours and 40 minutes.

Choose airline

Schedules

Air Europa

Non-stop with Air Europa

  • Total flight time: 8 hours and 40 minutes
  • Sky Team Alliance
  • Madrid is a Air Europa hub.
  • 1 flight per week
  • Boeing 787-8
  • Business class available
MAD
Direct
STI

The timetable & schedule information was updated at 2026-04-21

American Airlines

Via Miami with American Airlines

  • Total flight time: 13h 40m - 14h 55m.
  • One World Alliance
  • 15 flights per week
MAD
 
Via MIA
 
STI

The timetable & schedule information was updated at 2026-04-21

Delta Air Lines

Via New York with Delta Air Lines

  • Total flight time: 15h 47m - 16h 02m.
  • Sky Team Alliance
  • 14 flights per week
MAD
 
Via JFK
 
STI

The timetable & schedule information was updated at 2026-04-21

JetBlue Airways

Via Boston with JetBlue Airways

  • Total flight time: 15h 54m - 17h 51m.
  • Low-cost airline
MAD
 
Via BOS
 
STI

The timetable & schedule information was updated at 2026-04-21

Staying up-to-date with the airlines

At Airlineinformation.com you can learn all about the airlines operating around the world together with their destinations and where they operate. You will get a transparent overview of airlines with scheduled flights between any two destinations with non-stop or 1-stop flights regardless of price or availability.
Flight data on this page was last updated on 2026-06-02