Airlines with flights from New York to Knoxville
There are four airlines with scheduled flights between LGA and TYS. Both Delta and American Airlines operates non-stop flights from La Guardia to Mc Ghee Tyson and the flight time is 2 hours and 18 minutes.
Choose airline
Schedules
Non-stop with Delta Air Lines
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Total flight time: 2 hours and 18 minutes
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Sky Team Alliance
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New York is a Delta Air Lines hub.
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21 flights per week
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Canadair (Bombardier) Regional Jet 900
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First class available
Flight
The timetable & schedule information was updated at 2026-04-21
Non-stop with American Airlines
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Total flight time: 2 hours and 17 minutes
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One World Alliance
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6 flights per week
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First class available
Flight
The timetable & schedule information was updated at 2026-04-21
Via Washington with American Airlines
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Total flight time: 3h 44m - 6h 29m.
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One World Alliance
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114 flights per week
Flight
AA5647
AA5276
AA5276
AA5484
AA5484
The timetable & schedule information was updated at 2026-04-21
Via Charlotte with American Airlines
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Total flight time: 3h 53m - 6h 32m.
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One World Alliance
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181 flights per week
Flight
AA5950
AA5027
AA5953
AA5890
AA5027
AA5953
AA5831
AA6439
AA5957
AA5909
AA5511
AA5511
The timetable & schedule information was updated at 2026-04-21
Via Dulles with United Airlines
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Total flight time: 3h 55m - 5h 56m.
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91 flights per week
Flight
UA4257
UA6110
UA4914
UA4304
The timetable & schedule information was updated at 2026-04-21
Via Detroit with Delta Air Lines
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Total flight time: 4h 00m - 6h 39m.
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Sky Team Alliance
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New York is a Delta Air Lines hub.
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43 flights per week
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Canadair (Bombardier) Regional Jet 900
Flight
DL5347
DL4698
DL4941
DL5138
The timetable & schedule information was updated at 2026-04-21

There are four airlines with scheduled flights between LGA and TYS. Both Delta and American Airlines operates non-stop flights from La Guardia to Mc Ghee Tyson and the flight time is 2 hours and 18 minutes.
Via Nashville with Southwest