Airlines with flights from New York to Knoxville

There are four airlines with scheduled flights between LGA and TYS. Both Delta and American Airlines operates non-stop flights from La Guardia to Mc Ghee Tyson and the flight time is 2 hours and 18 minutes.

Choose airline

Schedules

Delta Air Lines

Non-stop with Delta Air Lines

  • Total flight time: 2 hours and 18 minutes
  • Sky Team Alliance
  • New York is a Delta Air Lines hub.
  • 21 flights per week
  • Canadair (Bombardier) Regional Jet 900
  • First class available
LGA
Direct
TYS

The timetable & schedule information was updated at 2026-04-21

American Airlines

Non-stop with American Airlines

  • Total flight time: 2 hours and 17 minutes
  • One World Alliance
  • 6 flights per week
  • First class available
LGA
Direct
TYS

The timetable & schedule information was updated at 2026-04-21

American Airlines

Via Washington with American Airlines

  • Total flight time: 3h 44m - 6h 29m.
  • One World Alliance
  • 114 flights per week
LGA
 
Via DCA
 
TYS
 
Flight
Mon
Jun 8
Tue
Jun 9
Wed
Jun 10
Thu
Jun 11
Fri
Jun 12
Sat
Jun 13
Sun
Jun 14
AA4612
AA5647
06:15
06:15
06:15
06:15
06:15
----
----
AA4654
AA5276
----
----
----
----
----
10:37
----
AA4590
AA5276
13:29
13:30
13:29
13:29
13:29
----
13:30
AA4685
AA5484
----
----
----
----
----
15:30
----
AA4773
AA5484
17:13
17:13
17:13
17:13
17:13
----
17:29
SHOW RETURN SCHEDULE
CHECK PRICES FOR LGA - TYS

The timetable & schedule information was updated at 2026-04-21

American Airlines

Via Charlotte with American Airlines

  • Total flight time: 3h 53m - 6h 32m.
  • One World Alliance
  • 181 flights per week
LGA
 
Via CLT
 
TYS
 
Flight
Mon
Jun 8
Tue
Jun 9
Wed
Jun 10
Thu
Jun 11
Fri
Jun 12
Sat
Jun 13
Sun
Jun 14
AA3084
AA5950
06:00
06:00
06:00
06:00
06:00
06:00
06:00
AA3279
AA5027
----
----
----
----
06:50
----
06:50
AA3279
AA5953
06:50
06:50
06:50
06:50
----
----
----
AA1023
AA5890
----
----
----
----
----
07:55
----
AA1023
AA5027
----
----
----
----
07:55
----
07:55
AA1023
AA5953
07:55
07:55
07:55
07:55
----
----
----
AA2043
AA5831
10:00
09:59
10:00
10:00
10:00
----
10:00
AA1150
AA6439
12:10
12:10
12:10
12:10
12:10
12:10
12:10
AA2033
AA5957
14:31
----
14:31
14:31
14:31
14:31
14:31
AA1320
AA5909
17:00
17:00
17:00
17:00
17:00
17:00
16:59
AA1942
AA5511
18:09
18:09
18:09
18:09
18:09
----
18:09
AA2856
AA5511
----
----
----
----
----
18:16
----
SHOW RETURN SCHEDULE
CHECK PRICES FOR LGA - TYS

The timetable & schedule information was updated at 2026-04-21

United Airlines

Via Dulles with United Airlines

  • Total flight time: 3h 55m - 5h 56m.
  • 91 flights per week
LGA
 
Via IAD
 
TYS

The timetable & schedule information was updated at 2026-04-21

Delta Air Lines

Via Detroit with Delta Air Lines

  • Total flight time: 4h 00m - 6h 39m.
  • Sky Team Alliance
  • New York is a Delta Air Lines hub.
  • 43 flights per week
  • Canadair (Bombardier) Regional Jet 900
LGA
 
Via DTW
 
TYS

The timetable & schedule information was updated at 2026-04-21

Staying up-to-date with the airlines

At Airlineinformation.com you can learn all about the airlines operating around the world together with their destinations and where they operate. You will get a transparent overview of airlines with scheduled flights between any two destinations with non-stop or 1-stop flights regardless of price or availability.
Flight data on this page was last updated on 2026-05-25