Airlines with flights from New York to Saint Louis

There are five airlines with scheduled flights between LGA and STL. Delta, Southwest and American Airlines has non-stop flights from La Guardia to Saint Louis Airport and the flight time is 2 hours and 54 minutes.

Change direction

Choose airline

Direct

$Delta Air Lines from {( $airportFrom->city_name }} to Saint Louis$

Non-stop

2h 54min

Direct

$Southwest Airlines from {( $airportFrom->city_name }} to Saint Louis$

Non-stop

2h 55min

Direct

$American Airlines from {( $airportFrom->city_name }} to Saint Louis$

Non-stop

2h 52min

Via Washington

4h 15min

Via Detroit

4h 26min

Via Chicago

4h 27min

Via Charlotte

4h 30min

Via Chicago

4h 30min

Via Chicago

4h 32min

Via Nashville

4h 40min

Via Atlanta

4h 43min

Via Dulles

4h 43min

Via Boston

5h 2min

Via Minneapolis

5h 3min

Via Kansas City

5h 20min

Via Atlanta

5h 29min

NEW

Via Charleston

7h 45min

Starts 06/06

Via Omaha

6h 25min

Starts 06/08

Via Atlanta

7h 45min

Starts 03/10

Via Minneapolis

8h 50min

Schedules

Non-stop with Delta Air Lines

Total flight time: 2 hours and 54 minutes
Sky Team Alliance
New York is a Delta Air Lines hub.

42 flights per week
Canadair (Bombardier) Regional Jet 900
First class available

LGA

Direct

STL

Flight

Mon

Jun 15

Tue

Jun 16

Wed

Jun 17

Thu

Jun 18

Fri

Jun 19

Sat

Jun 20

Sun

Jun 21

DL4939

06:30

----

DL4922

09:59

10:29

09:59

DL4905

13:59

DL4926

18:51

----

18:51

SHOW RETURN SCHEDULE

CLOSE RETURN SCHEDULE

CHECK PRICES FOR LGA - STL

The timetable & schedule information was updated at 2026-04-21

Non-stop with Southwest Airlines

Total flight time: 2 hours and 55 minutes
Low-cost airline

33 flights per week
Boeing 737MAX 8 Passenger

Boeing 737-800 (winglets) Passenger/BBJ2

Boeing 737-700 Passenger (Scimitar Winglets)

LGA

Direct

STL

Flight

Mon

Jun 15

Tue

Jun 16

Wed

Jun 17

Thu

Jun 18

Fri

Jun 19

Sat

Jun 20

Sun

Jun 21

WN523

08:55

06:30

08:55

----

WN1717

----

08:15

----

WN652

----

09:00

WN339

----

10:30

WN2473

12:00

10:45

12:00

WN473

----

15:00

WN2740

15:00

15:05

15:00

----

WN4895

18:30

17:45

18:30

17:20

18:35

SHOW RETURN SCHEDULE

CLOSE RETURN SCHEDULE

CHECK PRICES FOR LGA - STL

The timetable & schedule information was updated at 2026-04-21

Non-stop with American Airlines

Total flight time: 2 hours and 52 minutes
One World Alliance

19 flights per week
Embraer 175

Embraer 170
First class available

LGA

Direct

STL

Flight

Mon

Jun 15

Tue

Jun 16

Wed

Jun 17

Thu

Jun 18

Fri

Jun 19

Sat

Jun 20

Sun

Jun 21

AA4508

07:00

06:40

07:00

----

AA4509

12:30

12:00

12:30

12:50

14:25

12:50

AA4728

18:59

----

18:59

SHOW RETURN SCHEDULE

CLOSE RETURN SCHEDULE

CHECK PRICES FOR LGA - STL

The timetable & schedule information was updated at 2026-04-21

Via Washington with American Airlines

Total flight time: 4h 15m - 6h 50m.
One World Alliance

84 flights per week
Embraer 175

Embraer 170

LGA

Via DCA

STL

Flight

Mon

Jun 15

Tue

Jun 16

Wed

Jun 17

Thu

Jun 18

Fri

Jun 19

Sat

Jun 20

Sun

Jun 21

AA4612
AA5413

06:15

----

AA4654
AA5582

11:00

10:59