Airlines with flights from Houston to Knoxville

There are three airlines with scheduled flights between IAH and TYS. United is the only airline with non-stop flights from Houston Airport to Mc Ghee Tyson and the flight time is 2 hours and 19 minutes.

Choose airline

Schedules

United Airlines

Non-stop with United Airlines

  • Total flight time: 2 hours and 19 minutes
  • Houston is a United Airlines hub.
  • 21 flights per week
  • Embraer 175 (Enhanced Winglets)
  • First class available
IAH
Direct
TYS

The timetable & schedule information was updated at 2026-04-21

Delta Air Lines

Via Atlanta with Delta Air Lines

  • Total flight time: 3h 41m - 6h 20m.
  • Sky Team Alliance
  • 191 flights per week
IAH
 
Via ATL
 
TYS
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
DL1069
DL1743
05:40
05:40
05:40
05:40
05:40
----
05:40
DL1069
DL4724
----
----
----
----
----
05:40
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DL1315
DL4724
07:00
07:00
07:00
07:00
07:00
07:00
07:00
DL644
DL4724
08:05
08:05
08:05
08:05
08:05
----
08:05
DL1585
DL1148
09:42
09:42
09:42
09:42
09:42
----
09:42
DL1682
DL2571
12:13
12:13
12:13
12:13
12:13
----
12:13
DL1682
DL4641
----
----
----
----
----
12:13
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DL1572
DL5203
14:43
14:43
14:43
14:43
14:43
14:43
14:48
DL2890
DL5224
16:20
16:20
16:20
16:20
16:20
----
16:20
DL2890
DL2081
----
----
----
----
----
17:20
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DL1223
DL3072
18:37
----
----
18:37
18:37
----
18:37
DL1223
DL2081
----
18:37
18:37
----
----
----
----
SHOW RETURN SCHEDULE
CHECK PRICES FOR IAH - TYS

The timetable & schedule information was updated at 2026-04-21

American Airlines

Via Charlotte with American Airlines

  • Total flight time: 4h 09m - 6h 54m.
  • One World Alliance
  • 127 flights per week
IAH
 
Via CLT
 
TYS
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
AA2011
AA5953
06:02
06:02
06:02
06:02
----
----
----
AA3162
AA5831
08:47
08:47
08:47
08:47
08:47
08:47
08:47
AA1930
AA6439
10:18
10:18
10:18
10:18
10:18
10:18
10:18
AA1919
AA5909
15:04
15:06
15:06
15:06
15:04
15:06
15:06
AA1920
AA5511
17:29
----
----
17:29
17:29
17:43
17:29
SHOW RETURN SCHEDULE
CHECK PRICES FOR IAH - TYS

The timetable & schedule information was updated at 2026-04-21

American Airlines

Via Dallas with American Airlines

  • Total flight time: 4h 14m - 6h 40m.
  • One World Alliance
  • 155 flights per week
IAH
 
Via DFW
 
TYS
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
AA2551
AA5593
05:00
05:00
05:00
05:00
05:00
05:00
05:00
AA700
AA2873
06:02
06:02
06:02
06:02
06:02
06:02
06:02
AA3002
AA2873
07:00
07:00
07:00
07:00
07:00
07:00
07:00
AA3193
AA2876
09:28
09:28
09:28
09:28
09:28
----
09:28
AA1916
AA2876
10:37
10:37
10:37
10:37
10:37
10:37
10:37
AA3591
AA2876
11:24
11:19
11:24
11:24
11:24
11:24
11:24
AA2512
AA644
14:04
----
----
14:04
14:04
14:04
14:04
AA3583
AA5453
16:16
16:16
16:16
16:16
16:16
16:16
16:16
SHOW RETURN SCHEDULE
CHECK PRICES FOR IAH - TYS

The timetable & schedule information was updated at 2026-04-21

United Airlines

Via Dallas with United Airlines

  • Total flight time: 9h 28m - 9h 30m.
  • Houston is a United Airlines hub.
  • 13 flights per week
  • Embraer 175 (Enhanced Winglets)
IAH
 
Via DFW
 
TYS

The timetable & schedule information was updated at 2026-04-21

Staying up-to-date with the airlines

At Airlineinformation.com you can learn all about the airlines operating around the world together with their destinations and where they operate. You will get a transparent overview of airlines with scheduled flights between any two destinations with non-stop or 1-stop flights regardless of price or availability.
Flight data on this page was last updated on 2026-06-02