Airlines with flights from Detroit to Saint Louis

There are four airlines with scheduled flights between DTW and STL. Both Delta and Southwest operates non-stop flights from Detroit Metropolitan Airport to Saint Louis Airport and the flight time is 1 hour and 40 minutes.

Choose airline

Schedules

Delta Air Lines

Non-stop with Delta Air Lines

  • Total flight time: 1 hour and 40 minutes
  • Sky Team Alliance
  • Detroit is a Delta Air Lines hub.
  • 43 flights per week
  • Boeing 717-200
  • First class available
DTW
Direct
STL

The timetable & schedule information was updated at 2026-04-21

Southwest Airlines

Non-stop with Southwest Airlines

  • Total flight time: 1 hour and 45 minutes
  • Low-cost airline
  • 18 flights per week
  • Boeing 737-700 Passenger (Scimitar Winglets)
    Boeing 737MAX 8 Passenger
DTW
Direct
STL

The timetable & schedule information was updated at 2026-04-21

Southwest Airlines

Via Chicago with Southwest Airlines

  • Total flight time: 3h 05m - 5h 15m.
  • Low-cost airline
  • 87 flights per week
  • Boeing 737-700 Passenger (Scimitar Winglets)
    Boeing 737MAX 8 Passenger
DTW
 
Via MDW
 
STL

The timetable & schedule information was updated at 2026-04-21

American Airlines

Via Chicago with American Airlines

  • Total flight time: 3h 21m - 5h 54m.
  • One World Alliance
  • 129 flights per week
DTW
 
Via ORD
 
STL

The timetable & schedule information was updated at 2026-04-21

Southwest Airlines

Via Nashville with Southwest Airlines

  • Total flight time: 3h 35m - 5h 55m.
  • Low-cost airline
  • 50 flights per week
  • Boeing 737-700 Passenger (Scimitar Winglets)
    Boeing 737MAX 8 Passenger
DTW
 
Via BNA
 
STL
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
WN1708
WN1371
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10:40
10:40
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WN1775
WN1371
10:45
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10:45
10:45
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11:30
WN244
WN682
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19:55
WN643
WN682
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20:10
20:10
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WN1776
WN682
21:15
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21:15
21:15
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SHOW RETURN SCHEDULE
CHECK PRICES FOR DTW - STL

The timetable & schedule information was updated at 2026-04-21

United Airlines

Via Chicago with United Airlines

  • Total flight time: 3h 45m - 6h 06m.
  • 228 flights per week
DTW
 
Via ORD
 
STL
 
Flight
Mon
Jun 15
Tue
Jun 16
Wed
Jun 17
Thu
Jun 18
Fri
Jun 19
Sat
Jun 20
Sun
Jun 21
UA4754
UA4613
06:00
06:00
06:00
06:00
06:00
06:00
06:00
UA1355
UA4613
07:05
07:05
07:05
07:05
07:05
07:23
07:05
UA426
UA1355
08:50
08:50
08:50
08:50
08:50
08:50
08:50
UA1746
UA4581
11:05
11:05
11:05
11:00
11:00
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11:00
UA5550
UA4581
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----
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----
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11:00
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UA5381
UA4552
14:10
14:10
14:10
14:10
14:10
14:10
14:10
UA4673
UA4416
16:10
16:10
16:10
16:10
16:10
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16:10
UA5264
UA2144
18:10
18:10
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18:10
18:10
18:15
18:10
UA5264
UA2471
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18:10
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UA5552
UA4576
19:32
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19:32
19:32
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19:32
UA3593
UA4576
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19:32
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UA3556
UA4472
21:12
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21:12
21:12
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21:12
SHOW RETURN SCHEDULE
CHECK PRICES FOR DTW - STL

The timetable & schedule information was updated at 2026-04-21

Staying up-to-date with the airlines

At Airlineinformation.com you can learn all about the airlines operating around the world together with their destinations and where they operate. You will get a transparent overview of airlines with scheduled flights between any two destinations with non-stop or 1-stop flights regardless of price or availability.
Flight data on this page was last updated on 2026-06-02