Airlines with flights from Detroit to Saint Louis
There are four airlines with scheduled flights between DTW and STL. Both Delta and Southwest operates non-stop flights from Detroit Metropolitan Airport to Saint Louis Airport and the flight time is 1 hour and 40 minutes.
Choose airline
Schedules
Non-stop with Delta Air Lines
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Total flight time: 1 hour and 40 minutes
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Sky Team Alliance
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Detroit is a Delta Air Lines hub.
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43 flights per week
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Boeing 717-200
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First class available
Flight
The timetable & schedule information was updated at 2026-04-21
Non-stop with Southwest Airlines
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Total flight time: 1 hour and 45 minutes
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Low-cost airline
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18 flights per week
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Boeing 737-700 Passenger (Scimitar Winglets)Boeing 737MAX 8 Passenger
Flight
The timetable & schedule information was updated at 2026-04-21
Via Chicago with Southwest Airlines
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Total flight time: 3h 05m - 5h 15m.
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Low-cost airline
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87 flights per week
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Boeing 737-700 Passenger (Scimitar Winglets)Boeing 737MAX 8 Passenger
Flight
WN2901
WN2903
WN2905
The timetable & schedule information was updated at 2026-04-21
Via Chicago with American Airlines
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Total flight time: 3h 21m - 5h 54m.
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One World Alliance
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129 flights per week
Flight
AA6352
AA4537
AA439
AA1004
The timetable & schedule information was updated at 2026-04-21
Via Nashville with Southwest Airlines
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Total flight time: 3h 35m - 5h 55m.
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Low-cost airline
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50 flights per week
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Boeing 737-700 Passenger (Scimitar Winglets)Boeing 737MAX 8 Passenger
Flight
WN1371
WN1371
WN682
WN682
WN682
The timetable & schedule information was updated at 2026-04-21
Via Chicago with United Airlines
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Total flight time: 3h 45m - 6h 06m.
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228 flights per week
Flight
UA4613
UA4613
UA1355
UA4581
UA4581
UA4552
UA4416
UA2144
UA2471
UA4576
UA4576
UA4472
The timetable & schedule information was updated at 2026-04-21

There are four airlines with scheduled flights between DTW and STL. Both Delta and Southwest operates non-stop flights from Detroit Metropolitan Airport to Saint Louis Airport and the flight time is 1 hour and 40 minutes.