Airlines with flights from Detroit to San Diego

There are 6 airlines with scheduled flights between DTW and SAN. Delta is the only airline with non-stop flights from Detroit Metropolitan Airport to San Diego International Airport and the flight time is 4 hours and 48 minutes.

Choose airline

Schedules

Delta Air Lines

Non-stop with Delta Air Lines

  • Total flight time: 4 hours and 48 minutes
  • Sky Team Alliance
  • Detroit is a Delta Air Lines hub.
  • 23 flights per week
  • Boeing 757 Passenger
    Airbus A321
  • Business and first class available
DTW
Direct
SAN

The timetable & schedule information was updated at 2026-04-21

American Airlines

Via Phoenix with American Airlines

  • Total flight time: 5h 55m - 7h 57m.
  • One World Alliance
  • 66 flights per week
DTW
 
Via PHX
 
SAN

The timetable & schedule information was updated at 2026-04-21

Southwest Airlines

Via Saint Louis with Southwest Airlines

  • Total flight time: 5h 55m - 9h 45m.
  • Low-cost airline
  • 21 flights per week
DTW
 
Via STL
 
SAN

The timetable & schedule information was updated at 2026-04-21

Southwest Airlines

Via Chicago with Southwest Airlines

  • Total flight time: 6h 00m - 9h 50m.
  • Low-cost airline
  • 61 flights per week
DTW
 
Via MDW
 
SAN
 
Flight
Mon
Jul 13
Tue
Jul 14
Wed
Jul 15
Thu
Jul 16
Fri
Jul 17
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Jul 18
Sun
Jul 19
WN1781
WN2570
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08:10
WN1781
WN4648
08:40
08:40
08:40
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WN3669
WN4905
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08:55
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WN1781
WN2809
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08:55
08:55
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WN507
WN2883
13:25
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13:25
13:25
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WN1782
WN2884
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19:50
19:50
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19:20
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SHOW RETURN SCHEDULE
CHECK PRICES FOR DTW - SAN

The timetable & schedule information was updated at 2026-04-21

Southwest Airlines

Via Denver with Southwest Airlines

  • Total flight time: 6h 05m - 10h 10m.
  • Low-cost airline
  • 66 flights per week
DTW
 
Via DEN
 
SAN
 
Flight
Mon
Jul 13
Tue
Jul 14
Wed
Jul 15
Thu
Jul 16
Fri
Jul 17
Sat
Jul 18
Sun
Jul 19
WN1778
WN1699
05:25
05:25
05:25
05:55
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WN1778
WN1653
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05:30
WN1778
WN2689
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06:00
06:00
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WN4450
WN1703
16:00
17:25
17:25
16:00
16:00
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WN4159
WN1703
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17:20
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WN4450
WN1704
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18:35
SHOW RETURN SCHEDULE
CHECK PRICES FOR DTW - SAN

The timetable & schedule information was updated at 2026-04-21

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Flight data on this page was last updated on 2026-06-29