Airlines with flights from Detroit to San Diego
There are 6 airlines with scheduled flights between DTW and SAN. Delta is the only airline with non-stop flights from Detroit Metropolitan Airport to San Diego International Airport and the flight time is 4 hours and 48 minutes.
Choose airline
Schedules
Non-stop with Delta Air Lines
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Total flight time: 4 hours and 48 minutes
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Sky Team Alliance
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Detroit is a Delta Air Lines hub.
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23 flights per week
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Boeing 757 PassengerAirbus A321
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Business and first class available
DTW
Direct
SAN
W29, Jul 13 - Jul 19
Flight
Mon
Jul 13
Tue
Jul 14
Wed
Jul 15
Thu
Jul 16
Fri
Jul 17
Sat
Jul 18
Sun
Jul 19
DL492
08:45
08:45
08:45
08:45
08:45
08:45
08:45
DL2155
12:30
12:30
12:30
12:30
12:30
12:30
12:30
DL369
16:35
16:35
16:35
16:35
16:35
16:35
16:35
DL700
20:23
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20:23
20:23
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20:23
The timetable & schedule information was updated at 2026-04-21
Via Phoenix with American Airlines
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Total flight time: 5h 55m - 7h 57m.
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One World Alliance
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66 flights per week
DTW
Via PHX
SAN
W29, Jul 13 - Jul 19
Flight
Mon
Jul 13
Tue
Jul 14
Wed
Jul 15
Thu
Jul 16
Fri
Jul 17
Sat
Jul 18
Sun
Jul 19
AA3141
AA2477
AA2477
08:10
08:10
08:10
08:10
08:10
08:10
08:10
AA1790
AA559
AA559
17:53
17:53
17:54
17:54
17:53
17:54
17:54
The timetable & schedule information was updated at 2026-04-21
Via Saint Louis with Southwest Airlines
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Total flight time: 5h 55m - 9h 45m.
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Low-cost airline
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21 flights per week
DTW
Via STL
SAN
W29, Jul 13 - Jul 19
Flight
Mon
Jul 13
Tue
Jul 14
Wed
Jul 15
Thu
Jul 16
Fri
Jul 17
Sat
Jul 18
Sun
Jul 19
WN1783
WN4283
WN4283
06:55
07:05
07:05
06:55
06:55
----
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WN2478
WN4283
WN4283
----
----
----
----
----
----
07:05
WN2003
WN2528
WN2528
----
----
----
----
----
17:25
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The timetable & schedule information was updated at 2026-04-21
Via Chicago with Southwest Airlines
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Total flight time: 6h 00m - 9h 50m.
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Low-cost airline
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61 flights per week
DTW
Via MDW
SAN
W29, Jul 13 - Jul 19
Flight
Mon
Jul 13
Tue
Jul 14
Wed
Jul 15
Thu
Jul 16
Fri
Jul 17
Sat
Jul 18
Sun
Jul 19
WN1781
WN2570
WN2570
----
----
----
----
----
----
08:10
WN1781
WN4648
WN4648
08:40
08:40
08:40
----
----
WN3669
WN4905
WN4905
----
----
----
----
----
08:55
----
WN1781
WN2809
WN2809
----
08:55
08:55
----
----
----
----
WN507
WN2883
WN2883
13:25
----
----
13:25
13:25
----
----
WN1782
WN2884
WN2884
----
19:50
19:50
----
----
19:20
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The timetable & schedule information was updated at 2026-04-21
Via Denver with Southwest Airlines
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Total flight time: 6h 05m - 10h 10m.
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Low-cost airline
-
66 flights per week
DTW
Via DEN
SAN
W29, Jul 13 - Jul 19
Flight
Mon
Jul 13
Tue
Jul 14
Wed
Jul 15
Thu
Jul 16
Fri
Jul 17
Sat
Jul 18
Sun
Jul 19
WN1778
WN1699
WN1699
05:25
05:25
05:25
05:55
----
WN1778
WN1653
WN1653
----
----
----
----
----
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05:30
WN1778
WN2689
WN2689
----
06:00
06:00
----
----
----
----
WN4450
WN1703
WN1703
16:00
17:25
17:25
16:00
16:00
----
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WN4159
WN1703
WN1703
----
----
----
----
----
17:20
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WN4450
WN1704
WN1704
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----
----
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18:35
The timetable & schedule information was updated at 2026-04-21

There are 6 airlines with scheduled flights between DTW and SAN. Delta is the only airline with non-stop flights from Detroit Metropolitan Airport to San Diego International Airport and the flight time is 4 hours and 48 minutes.
Via Phoenix with Frontier
Via Denver with United
Via Minneapolis with Sun Country Airlines