Airlines with flights from Detroit to Greenville

There are four airlines with scheduled flights between DTW and GSP. Delta is the only airline with non-stop flights from Detroit Metropolitan Airport to Greenville-Spartanburg International and the flight time is 1 hour and 43 minutes.

Choose airline

Schedules

Delta Air Lines

Non-stop with Delta Air Lines

  • Total flight time: 1 hour and 43 minutes
  • Sky Team Alliance
  • Detroit is a Delta Air Lines hub.
  • 20 flights per week
  • Canadair (Bombardier) Regional Jet 700 and Challenger 870
    Boeing 717-200
  • First class available
DTW
Direct
GSP

The timetable & schedule information was updated at 2026-04-21

American Airlines

Via Charlotte with American Airlines

  • Total flight time: 3h 11m - 5h 56m.
  • One World Alliance
  • 173 flights per week
DTW
 
Via CLT
 
GSP
 
Flight
Mon
Jul 6
Tue
Jul 7
Wed
Jul 8
Thu
Jul 9
Fri
Jul 10
Sat
Jul 11
Sun
Jul 12
AA387
AA5799
06:00
06:00
06:00
06:00
06:00
06:00
06:00
AA1439
AA5802
07:00
----
----
07:00
07:00
----
07:00
AA1791
AA5805
10:01
10:01
10:01
10:01
10:01
10:01
10:01
AA1781
AA5203
13:41
13:41
13:41
13:41
13:41
----
13:41
AA1770
AA5524
16:17
16:17
16:17
16:17
16:17
16:37
16:17
AA1794
AA5504
19:58
19:58
19:58
19:58
19:58
19:58
19:58
SHOW RETURN SCHEDULE
CHECK PRICES FOR DTW - GSP

The timetable & schedule information was updated at 2026-04-21

American Airlines

Via Washington with American Airlines

  • Total flight time: 3h 27m - 6h 01m.
  • One World Alliance
  • 34 flights per week
DTW
 
Via DCA
 
GSP

The timetable & schedule information was updated at 2026-04-21

Delta Air Lines

Via Atlanta with Delta Air Lines

  • Total flight time: 3h 30m - 6h 00m.
  • Sky Team Alliance
  • Detroit is a Delta Air Lines hub.
  • 270 flights per week
  • Canadair (Bombardier) Regional Jet 700 and Challenger 870
    Boeing 717-200
DTW
 
Via ATL
 
GSP
 
Flight
Mon
Jul 6
Tue
Jul 7
Wed
Jul 8
Thu
Jul 9
Fri
Jul 10
Sat
Jul 11
Sun
Jul 12
DL2375
DL3089
----
05:20
05:20
05:20
05:20
05:20
05:20
DL1611
DL2158
----
06:20
06:20
06:20
06:20
----
06:20
DL1611
DL1725
06:20
----
----
----
----
----
----
DL965
DL1725
07:20
07:20
07:20
07:20
07:20
07:20
07:20
DL1653
DL1725
08:25
08:25
08:25
08:25
08:25
08:25
08:25
DL2777
DL1273
09:25
09:25
09:25
09:25
09:25
09:25
09:25
DL2856
DL1273
10:25
10:25
10:25
10:25
10:25
10:25
10:31
DL2188
DL3095
12:25
12:25
12:25
12:25
12:25
12:25
12:25
DL1228
DL1021
14:58
14:59
14:59
14:59
14:59
----
14:59
DL1467
DL1021
----
----
----
----
----
14:59
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DL1467
DL2319
16:00
15:59
15:59
15:59
15:59
----
15:59
DL2053
DL2281
18:38
18:38
18:38
18:38
18:38
17:59
18:38
DL2294
DL2281
----
----
----
----
----
19:45
----
SHOW RETURN SCHEDULE
CHECK PRICES FOR DTW - GSP

The timetable & schedule information was updated at 2026-04-21

Southwest Airlines

Via Nashville with Southwest Airlines

  • Total flight time: 3h 30m - 6h 55m.
  • Low-cost airline
  • 26 flights per week
DTW
 
Via BNA
 
GSP

The timetable & schedule information was updated at 2026-04-21

Staying up-to-date with the airlines

At Airlineinformation.com you can learn all about the airlines operating around the world together with their destinations and where they operate. You will get a transparent overview of airlines with scheduled flights between any two destinations with non-stop or 1-stop flights regardless of price or availability.
Flight data on this page was last updated on 2026-06-22