Airlines with flights from Denver to Greenville

There are four airlines with scheduled flights between DEN and GSP. United is the only airline with non-stop flights from Denver International to Greenville-Spartanburg International and the flight time is 3 hours and 7 minutes.

Choose airline

Schedules

United Airlines

Non-stop with United Airlines

  • Total flight time: 3 hours and 7 minutes
  • Denver is a United Airlines hub.
  • 6 flights per week
  • Airbus A320
  • First class available
DEN
Direct
GSP

The timetable & schedule information was updated at 2026-04-21

Southwest Airlines

Via Nashville with Southwest Airlines

  • Total flight time: 4h 20m - 8h 50m.
  • Low-cost airline
  • Denver is a Southwest Airlines focus city (Operating base).
  • 135 flights per week
DEN
 
Via BNA
 
GSP
 
Flight
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Jul 13
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WN3946
WN4622
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05:00
WN1483
WN4622
05:45
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05:45
05:45
05:35
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WN3456
WN4622
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05:40
05:40
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WN1485
WN526
10:00
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10:00
10:00
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10:05
WN1485
WN2089
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10:15
10:15
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WN2707
WN4007
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10:35
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WN2010
WN526
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11:30
WN1712
WN4007
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11:40
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WN1266
WN4563
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11:55
11:55
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WN4301
WN4007
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11:55
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WN1486
WN2089
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12:00
12:00
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WN1712
WN4563
12:55
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12:55
12:55
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WN1657
WN4563
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13:00
13:00
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WN1652
WN4006
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13:20
WN1768
WN4006
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13:35
WN3193
WN4563
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13:35
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WN1768
WN4563
14:20
13:35
13:35
14:20
14:20
13:35
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WN2264
WN4563
13:45
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13:45
13:45
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WN2264
WN4006
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13:50
WN2452
WN4563
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14:00
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WN2373
WN4563
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14:00
14:00
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WN1486
WN4563
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14:35
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WN2597
WN4563
15:15
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15:15
15:15
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WN1488
WN4563
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15:25
15:25
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WN2597
WN4006
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15:55
SHOW RETURN SCHEDULE
CHECK PRICES FOR DEN - GSP

The timetable & schedule information was updated at 2026-04-21

Delta Air Lines

Via Atlanta with Delta Air Lines

  • Total flight time: 4h 28m - 7h 05m.
  • Sky Team Alliance
  • 193 flights per week
DEN
 
Via ATL
 
GSP
 
Flight
Mon
Jul 13
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Jul 15
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Jul 17
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Jul 18
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Jul 19
DL302
DL3089
00:40
00:40
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00:40
00:40
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DL341
DL1273
06:00
06:00
06:00
06:00
06:00
06:00
06:00
DL431
DL1273
07:15
07:15
07:15
07:15
07:15
07:15
07:15
DL346
DL1021
10:52
10:52
10:52
10:52
10:52
10:52
10:52
DL824
DL2319
13:10
13:10
13:10
13:10
13:10
13:10
13:10
DL706
DL3136
14:10
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14:10
14:10
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14:10
DL957
DL2281
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15:10
15:10
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15:10
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DL957
DL3136
15:10
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15:10
15:10
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15:10
DL840
DL2281
16:35
16:35
16:35
16:35
16:35
16:35
16:35
SHOW RETURN SCHEDULE
CHECK PRICES FOR DEN - GSP

The timetable & schedule information was updated at 2026-04-21

American Airlines

Via Charlotte with American Airlines

  • Total flight time: 4h 49m - 7h 21m.
  • One World Alliance
  • 123 flights per week
DEN
 
Via CLT
 
GSP
 
Flight
Mon
Jul 13
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Jul 17
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Jul 18
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Jul 19
AA573
AA5805
06:41
06:41
06:41
06:41
06:41
06:41
06:41
AA1754
AA5203
10:00
10:00
10:00
10:00
10:00
10:00
10:00
AA1758
AA5524
13:57
13:57
13:57
13:57
13:57
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13:57
AA1735
AA5504
15:57
15:57
15:57
15:57
15:57
15:57
15:57
AA3156
AA5798
23:59
23:59
23:59
23:59
23:59
23:59
23:59
SHOW RETURN SCHEDULE
CHECK PRICES FOR DEN - GSP

The timetable & schedule information was updated at 2026-04-21

American Airlines

Via Chicago with American Airlines

  • Total flight time: 5h 00m - 7h 36m.
  • One World Alliance
  • 55 flights per week
DEN
 
Via ORD
 
GSP

The timetable & schedule information was updated at 2026-04-21

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At Airlineinformation.com you can learn all about the airlines operating around the world together with their destinations and where they operate. You will get a transparent overview of airlines with scheduled flights between any two destinations with non-stop or 1-stop flights regardless of price or availability.
Flight data on this page was last updated on 2026-06-29