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American Airlines flights from Buffalo (BUF)

American Airlines operates nonstop flights to 11 destinations from Buffalo (BUF), offering 168 weekly departures. All nonstop routes are domestic within USA.

American Airlines routes from BUF

American Airlines routes from Buffalo (BUF)

Explore nonstop destinations served by American Airlines from Buffalo (BUF).

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American Airlines departures from Buffalo Niagara International, BUF

Monday
Mon
Jun 22
22 flights
Tuesday
Tue
Jun 23
21 flights
Wednesday
Wed
Jun 24
22 flights
Thursday
Thu
Jun 25
21 flights
Friday
Fri
Jun 26
21 flights
Saturday
Sat
Jun 27
19 flights
Sunday
Sun
Jun 28
21 flights
Time
To
Flight
05:00
AA5051
05:25
AA5873
06:00
AA1195
06:02
AA4522
06:26
AA1204
07:00
AA4788
07:01
AA882
08:06
AA2112
10:01
AA4413
10:44
AA5925
11:03
AA4379
11:22
AA4666
12:49
AA5104
13:46
AA1616
14:47
AA6041
16:10
AA4440
16:47
AA1615
16:55
AA5106
16:57
AA4913
18:21
AA4378
19:32
AA1614
19:40
AA6114
05:00
AA5051
05:25
AA5873
06:00
AA1195
06:02
AA4522
06:26
AA1204
07:00
AA4788
07:01
AA882
08:06
AA2112
10:01
AA4413
10:44
AA5925
11:03
AA4379
11:22
AA4666
12:49
AA5104
13:46
AA1616
14:47
AA6041
16:10
AA4440
16:55
AA5106
16:57
AA4913
18:21
AA4378
19:32
AA1614
19:40
AA6114
05:00
AA5051
05:25
AA5873
06:00
AA1195
06:02
AA4522
06:26
AA1204
07:00
AA4788
07:01
AA882
08:06
AA2112
10:01
AA4413
10:44
AA5925
11:03
AA4379
11:22
AA4666
12:49
AA5104
13:46
AA1616
14:47
AA6041
16:10
AA4440
16:47
AA1615
16:55
AA5106
16:57
AA4913
18:21
AA4378
19:32
AA1614
19:40
AA6114
05:00
AA5051
05:25
AA5873
06:00
AA1195
06:02
AA4522
06:26
AA1204
07:00
AA4788
07:01
AA882
08:06
AA2112
10:01
AA4413
10:44
AA5925
11:03
AA4379
11:22
AA4666
12:49
AA5104
13:46
AA1616
14:47
AA6041
16:10
AA4440
16:55
AA5106
16:57
AA4913
18:21
AA4378
19:32
AA1614
19:40
AA6114
05:00
AA5051
05:25
AA5873
06:00
AA1195
06:02
AA4522
06:26
AA1204
07:00
AA4788
07:01
AA882
08:06
AA2112
10:01
AA4413
10:44
AA5925
11:03
AA4379
11:22
AA4666
12:49
AA5104
13:46
AA1616
14:47
AA6041
16:46
AA1615
16:55
AA5106
16:57
AA4913
18:21
AA4378
19:32
AA1614
19:40
AA6114
05:25
AA5873
05:36
AA5051
06:00
AA1195
06:06
AA1204
07:01
AA882
07:07
AA4522
07:45
AA4788
08:06
AA2112
10:01
AA4413
10:19
AA4666
10:44
AA5925
11:22
AA4379
12:29
AA5104
13:46
AA1616
14:47
AA6041
16:49
AA5106
16:59
AA4913
19:30
AA1614
19:40
AA6114
05:33
AA4482
06:00
AA1195
06:19
AA4788
06:26
AA1204
07:01
AA882
08:06
AA2112
08:29
AA4522
10:01
AA4413
10:44
AA5925
11:00
AA4666
12:32
AA4379
12:41
AA5104
13:46
AA1616
14:47
AA6041
16:10
AA4440
16:47
AA1615
16:57
AA4913
17:34
AA5106
18:18
AA4378
19:32
AA1614
19:40
AA6114
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Flight data on this page was last updated on 2026-06-08